Cold vs Warm Enteral Feeding and Gastric Emptying in Adult ICU Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: enteral nutrition, enteral nutrition.
- Who it may be relevant to
- Registry conditions: Gastric Emptying, Enteral Nutrition (Food for Special Medical Purposes). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of Cold and Warm Enteral Feeding on Gastric Emptying in Adult Intensive Care Patients: A Cross-Over Study
Overview
In critically ill patients receiving enteral nutrition in the intensive care unit, the functional capacity of the gastrointestinal system can be significantly influenced by the mode of nutritional support. The temperature of enteral feeding may exert potential effects on gastric emptying, intestinal motility, and nutrient absorption. However, the existing literature on the impact of feeding temperature is limited, and randomized or cross-over controlled studies directly comparing warm and cold enteral feeding are scarce. This study aims to systematically evaluate the effects of enteral feeding temperature on feeding tolerance (vomiting and aspiration), gastric emptying rate (gastric residual volume), and the incidence of diarrhea, thereby providing evidence to inform clinical practice.
Interventions
- Dietary supplement enteral nutrition
Cold enteral feeding (24-25 degree), warm enteral feeding (36-37 degree) - Dietary supplement enteral nutrition
cold enteral nutrition
Primary outcome measures
- Gastric volume measured by ultrasonography at 60, 90, 120, 180, 240, 360, and 480 minutes after administration of cold and warm enteral feeding. [Time frame: Baseline (0 minutes) and up to 480 minutes after enteral feeding]
Eligibility criteria
Inclusion criteria
- Patients aged 18 years or older
- Expected length of stay in the intensive care unit of at least 96 hours
- Patients receiving enteral nutrition via a nasogastric tube
- Absence of ileus or active gastrointestinal bleeding
Exclusion criteria
- Patients younger than 18 years of age
- Use of high-dose opioids known to affect gastrointestinal motility
- Patients receiving parenteral nutrition
- Known gastrointestinal diseases or a history of gastrointestinal surgery
- Patients with acute intracranial events will not be included in the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Crossover
- Masking
- Single blind
- Primary purpose
- Prevention
Study locations
Turkey (Türkiye) · 1 center
- Bursa Yuksek Ihtisas Research and Education Hospital — Bursa
Identifiers
NCT: NCT07415616 · 2024-TBEK 2025/08-17