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Recruiting NCT07415109

Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages

No phase Interventional Adherence Preventive Health Services

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: General Message, Personalized Message.
Who it may be relevant to
Registry conditions: Adherence, Preventive Health Services. Basic parameters: 21 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Singapore
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages: A Three-Arm Randomized Controlled Trial

Overview

The study is meant to run parallel to the larger study, RESET. The goal of this study is to to evaluate the effectiveness of a once-off general and personality-tailored text message on GP consultation among RESET participants identified to have high LDL-C. The main question it aims to answer is: Will participants exposed to personality tailored advice have a higher adherence to GP consultation compared to the participants in the control group? Researchers will compare a personalized message to a general message (with no personalization according to patients personality type) and control group to see if the messages increase adherence. Participants are required to complete two questionnaires: one before and one after they receive their RESET results.

Interventions

  • Behavioral General Message
    The intervention will consist of messages and infographics embedded in participants' return of results (ROR) emails within the RESET study. Each participant will receive the ROR alongside the intervention once, at the time their results are sent. No repeat messages will be delivered. The general health message will include indications for lipid therapy, benefits of lipid-lowering medications, common side effects, risks of non-adherence, and an infographic on diet and lifestyle modification base
  • Behavioral Personalized Message
    The intervention will consist of messages and infographics embedded in participants' return of results (ROR) emails within the RESET study. Each participant will receive the ROR alongside the intervention once, at the time their results are sent. No repeat messages will be delivered. The message will include the personality-tailored message with the same core content as the general message, including indications for lipid therapy, benefits of lipid-lowering medications, common side effects, ris

Primary outcome measures

  • Intention to adopt a healthier diet [Time frame: From enrollment to 3 months after results have been returned.]
  • Intention to engage in Physical Activity [Time frame: From enrollment to 3 months after results have been returned.]
  • Intention to visit a General Practitioner [Time frame: 3 months after results have been returned.]

Eligibility criteria

Inclusion criteria

  • New participants of RESET who have given consent to be contacted for future studies
  • ≥21 years old

Exclusion criteria

  • are not able to read, write or communicate in English

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Prevention

Study locations

Singapore · 1 center
  • National University of Singapore — Singapore

Identifiers

NCT: NCT07415109 · NUS-IRB-2025-334

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗