ASMact: Study on Management of Bronchial Asthma
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Asthma Acute, Asthma Childhood, Asthma in Children, Asthma Crisis. Basic parameters: 6 years — 17 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Standardization According to GINA 2025 Recommendations for the Treatment, Management, and Follow-up of Acute Asthma Attacks: Observational, Multicenter Cohort Study.
Overview
Standardization According to GINA 2025 Recommendations for the Treatment, Management, and Follow-up of Acute Asthma Attacks: Observational, Multicenter Cohort Study.
Detailed description
Patients aged 6 to 17 years presenting to the emergency department with an acute asthma exacerbation were included. Clinical outcomes were compared between a pre-intervention period (October 2024-May 2025) and a post-intervention period (October 2025-May 2026).
Between the two study periods, a structured educational intervention targeting medical and nursing staff was implemented. The intervention consisted of didactic lectures, clinical simulation sessions, case-based discussions, and the dissemination of updated diagnostic and therapeutic flowcharts based on the 2025 Global Initiative for Asthma (GINA) guidelines.
Primary outcome measures
- Change in the number of correctly reported diagnoses before and after intervention [Time frame: Pre-intervention and through study completion, an average of 9 months]
- Percentage of patients with correct timing, dosage, and method of drug administration before and after intervention [Time frame: Pre-intervention and through study completion, an average of 9 months]
- Percentage of patients with correct follow-up at discharge [Time frame: Pre-intervention and through study completion, an average of 9 months]
- Percentage of patients in whom additional drugs are used in refractory cases [Time frame: Pre-intervention and through study completion, an average of 9 months]
- Percentage of patients with correct therapy at discharge [Time frame: Pre-intervention and through study completion, an average of 9 months]
Secondary outcome measures (1)
- Incidence of acute asthma exacerbations [Time frame: Pre-intervention and through study completion, an average of 9 months]
Eligibility criteria
Inclusion criteria
- Age between 6 and 17 years
- Presentation to the emergency department with a diagnosis of acute asthma exacerbation
- Evaluation in the emergency department of one of the participating centers during the study periods
Exclusion criteria
- Age < 6 years or > 17 years
- Diagnosis other than acute asthma exacerbation
- Incomplete or missing clinical data
- Patients transferred from other hospitals already treated for the same episode
- history of allergy to any drugs used in the protocol
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Italy · 2 centers
- Arcispedale S. Anna — Ferrara
- Meyer Children's Hospital IRCCS, Firenze — Florence
Identifiers
NCT: NCT07412769 · ASMact