Menu
Recruiting NCT07411313

Internal Jugular Vein Ultrasound for Predicting Hypotension in Geriatric Patients Undergoing Spinal Anesthesia

Observational Spinal Anesthesia Induced Hypotension Geriatric Internal Jugular Vein Ultrasonography

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Not applicable- observational study.
Who it may be relevant to
Registry conditions: Spinal Anesthesia Induced Hypotension, Geriatric, Internal Jugular Vein, Ultrasonography. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Role of Internal Jugular Vein Ultrasonography in Predicting Hypotension in Geriatric Patients Undergoing Spinal Anesthesia: A Prospective Observational Study (Protocol ID: 2023-12/509)

Overview

Spinal anesthesia-induced hypotension is a common and clinically significant complication in geriatric patients. Accurate preoperative assessment of intravascular volume status may help identify patients at risk. Internal jugular vein (IJV) ultrasonography is a noninvasive and easily applicable bedside method that reflects venous volume status. This prospective observational study aims to evaluate the role of preoperative IJV ultrasonographic measurements in predicting hypotension following spinal anesthesia in geriatric patients. Patients aged 65 years and older undergoing elective surgery under spinal anesthesia will be included. Preoperative IJV diameter, cross-sectional area, and collapsibility index will be measured using ultrasonography. Hemodynamic parameters will be monitored intraoperatively, and the occurrence of hypotension after spinal anesthesia will be recorded. The predictive value of IJV ultrasonographic parameters for post-spinal hypotension will be analyzed

Detailed description

Spinal anesthesia is widely used in geriatric patients; however, hypotension following spinal anesthesia remains a frequent and clinically relevant complication in this population. Age-related physiological changes and reduced cardiovascular reserve increase susceptibility to hemodynamic instability. Therefore, identifying patients at risk of hypotension before spinal anesthesia is of clinical importance.

Assessment of intravascular volume status may contribute to predicting post-spinal hypotension. Ultrasonographic evaluation of the internal jugular vein (IJV) provides a noninvasive, bedside method reflecting venous filling and volume status. Parameters such as IJV diameter, cross-sectional area, and collapsibility index have been proposed as potential predictors of hypotension.

This prospective observational study will include patients aged 65 years and older undergoing elective surgery under spinal anesthesia. Preoperative ultrasonographic measurements of the IJV will be performed in the supine position prior to spinal anesthesia. Hemodynamic parameters, including systolic and diastolic blood pressure and heart rate, will be recorded before and after spinal anesthesia. Hypotension will be defined according to predefined criteria and documented during the intraoperative period.

The primary objective of the study is to evaluate the predictive value of preoperative IJV ultrasonographic measurements for hypotension following spinal anesthesia in geriatric patients.

Interventions

  • Other Not applicable- observational study
    Not applicable- observational study

Primary outcome measures

  • Post-spinal hypotension [Time frame: From spinal anesthesia administration up to 90 minutes intraoperatively.]

Eligibility criteria

Inclusion criteria

  • Age ≥65 years
  • Scheduled to undergo surgery under spinal anesthesia
  • American Society of Anesthesiologists (ASA) physical status I-III
  • Able and willing to provide written informed consent

Exclusion criteria

  • Did not provide written informed consent
  • Undergoing emergency surgery
  • Body mass index (BMI) ≥40 kg/m²
  • Receiving angiotensin-converting enzyme (ACE) inhibitors
  • Pre-spinal systolic blood pressure <90 mmHg or mean arterial pressure <70 mmHg
  • Unable to tolerate the supine position
  • Left ventricular ejection fraction <40%
  • Requiring sedoanalgesia in addition to spinal anesthesia or conversion to general anesthesia

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Turkey (Türkiye) · 1 center
  • Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital — Ankara

Publications

  • Kaur K, Sara H, Duggal G, Depuru A, Reddy A, Bansal N. The Use of the Internal Jugular Vein Collapsibility Index (IJVCI) for the Prediction of Postspinal Hypotension in Geriatric Patients Posted for Lower Limb Surgeries. Cureus. 2025 Jan 2;17(1):e76824. doi: 10.7759/cureus.76824. eCollection 2025 Jan. PMID 39897318
  • Klohr S, Roth R, Hofmann T, Rossaint R, Heesen M. Definitions of hypotension after spinal anaesthesia for caesarean section: literature search and application to parturients. Acta Anaesthesiol Scand. 2010 Sep;54(8):909-21. doi: 10.1111/j.1399-6576.2010.02239.x. Epub 2010 Apr 23. PMID 20455872
  • N P, Sinha M, Kumar M, Ramchandani S, Khetrapal M, Karoo K, Mesa BK. Role of Internal Jugular Vein Collapsibility Index in Predicting Post-spinal Hypotension in Pregnant Women Undergoing Cesarean Section: A Prospective Observational Study. Cureus. 2023 May 23;15(5):e39389. doi: 10.7759/cureus.39389. eCollection 2023 May. PMID 37362461
  • Wang MK, Piticaru J, Kappel C, Mikhaeil M, Mbuagbaw L, Rochwerg B. Internal jugular vein ultrasound for the diagnosis of hypovolemia and hypervolemia in acutely ill adults: a systematic review and meta-analysis. Intern Emerg Med. 2022 Aug;17(5):1521-1532. doi: 10.1007/s11739-022-03003-y. Epub 2022 Jun 20. PMID 35718838
  • Tsui BC, Wagner A, Finucane B. Regional anaesthesia in the elderly: a clinical guide. Drugs Aging. 2004;21(14):895-910. doi: 10.2165/00002512-200421140-00001. PMID 15554749
  • Critchley LA. Hypotension, subarachnoid block and the elderly patient. Anaesthesia. 1996 Dec;51(12):1139-43. doi: 10.1111/j.1365-2044.1996.tb15051.x. PMID 9038450
  • Hartmann B, Junger A, Klasen J, Benson M, Jost A, Banzhaf A, Hempelmann G. The incidence and risk factors for hypotension after spinal anesthesia induction: an analysis with automated data collection. Anesth Analg. 2002 Jun;94(6):1521-9, table of contents. doi: 10.1097/00000539-200206000-00027. PMID 12032019
  • Priebe HJ. The aged cardiovascular risk patient. Br J Anaesth. 2000 Nov;85(5):763-78. doi: 10.1093/bja/85.5.763. PMID 11094595

Identifiers

NCT: NCT07411313 · 2023-12/509

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗