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Not yet recruiting NCT07401602

Analgesic Strategies After Mastectomy: RIB vs RIB + DPIPB

Observational Postoperative Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Analgesic Strategy.
Who it may be relevant to
Registry conditions: Postoperative Pain. Basic parameters: 18 years — 70 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

A Retrospective Evaluation of Systemic Analgesia, Rhomboid Intercostal Block, and Combined Rhomboid Intercostal Block With Deep Parasternal Intercostal Plane Block After Mastectomy

Overview

This retrospective observational study evaluates postoperative pain outcomes in patients undergoing elective mastectomy who received systemic analgesia, rhomboid intercostal block (RIB), or combined rhomboid intercostal block with deep parasternal intercostal plane block (RIB + DPIPB). Medical records from October 2024 to October 2025 will be reviewed. Primary outcomes include pain scores within the first 24 hours, with secondary outcomes including opioid consumption, additional analgesic requirements, patient satisfaction, and early postoperative complications. All data will be analyzed retrospectively and anonymously.

Interventions

  • Other Analgesic Strategy
    Systemic Analgesia: Postoperative pain was managed using standard systemic analgesic medications as part of routine clinical care. Rhomboid Intercostal Block (RIB): Postoperative analgesia was provided using an ultrasound-guided rhomboid intercostal block performed as part of routine clinical practice. RIB + Deep Parasternal Intercostal Plane Block (DPIPB): Postoperative analgesia was provided using a combination of ultrasound-guided rhomboid intercostal block and deep parasternal intercost

Primary outcome measures

  • Postoperative Pain Score (VAS) [Time frame: Within the first 24 hours after surgery (postoperative 1, 6, 12, and 24 hours).]

Eligibility criteria

Inclusion criteria

  • Female patients aged 18-70 years
  • Elective mastectomy performed between October 2024 and October 2025
  • ASA physical status I-III
  • Complete postoperative pain and analgesia records for the first 24 hours
  • Clearly documented analgesic technique (systemic analgesia, RIB, or RIB + DPIPB)

Exclusion criteria

  • Incomplete or missing medical records
  • Emergency mastectomy or emergency surgery
  • Reoperation within the first 24 hours postoperatively
  • Major intraoperative complications preventing standard analgesia
  • Neurological or psychiatric conditions interfering with pain assessment

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-control

Study locations

Turkey (Türkiye) · 1 center
  • Istinye Üniversity — Istanbul

Publications

  • Ertas G, Cakmak HS, Ocak S, Yilmaz M, Ozdemir DB, Tulgar S. Is the combination of interfascial plane blocks sufficient for awake breast cancer surgery? An observational, prospective, proof-of-concept study. BMC Anesthesiol. 2024 Sep 20;24(1):337. doi: 10.1186/s12871-024-02725-0. PMID 39304815
  • Gu B, Huang ZX, Zhou HD, Lian YH, He S, Ge M, Jiang HF. A Randomized Controlled Trial of Adding Deep Parasternal Intercostal Plane Block to Interpectoral-Pectoserratus Plane Block in Breast Cancer Surgery. Anesth Analg. 2025 May 1;140(5):1188-1194. doi: 10.1213/ANE.0000000000007218. PMID 39453840

Identifiers

NCT: NCT07401602 · zeki mastektomi

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗