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Not yet recruiting NCT07401069

Homemade Herbal Mouthwash in Gingivitis. A Randomized Clinical Trial.

Phase III Interventional Gingivitis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Chlorhexidine 0,12%, herbal Mouthwash.
Who it may be relevant to
Registry conditions: Gingivitis. Basic parameters: from 20 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Effect of Homemade Herbal Mouthwash Versus Chlorhexidine on Plaque Accumulation in Gingivitis. A Randomized Clinical Trial.

Overview

Gingivitis is a very common oral disease that may progress to the more destructive periodontitis if not treated. As oral plaque is a key player in gingivitis, plaque control by professional scaling and oral hygiene measures represents the main line of treatment. Among the oral hygiene measures, using chlorhexidine mouthwash is considered the gold standard in mouthwashes. However, due to its side effects, a safer and more acceptable mouthwash is needed. Therefore, this study proposes mouthwashes made of infusion of natural herbs as an alternative.

Interventions

  • Drug Chlorhexidine 0,12%
    chlorhexidine 0.12% mouthwash twice daily for 7 days
  • Drug herbal Mouthwash
    Mouthwash made at home by boiling herbs in water and then saving the solution in a tightly closed container for daily use for 7 days

Primary outcome measures

  • plaque index (O'Leary et al., 1972) [Time frame: 7 days]
Secondary outcome measures (4)
  • Bleeding on probing [Time frame: 7 days]
  • Changes in clinical signs of inflammation (Armitage, 2004) [Time frame: 7 days]
  • Bleeding on brushing [Time frame: 7 days]
  • Patient's acceptance of the mouthwash [Time frame: 7 days]

Eligibility criteria

Inclusion criteria

  • Plaque-induced gingivitis.

Exclusion criteria

  • Medically compromised.
  • History of medications.
  • Pregnant females.
  • Periapical involvement in teeth.
  • History of periodontal surgery.
  • If gingivitis was due to local factor.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07401069 · ACU-Per3

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗