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Recruiting NCT07392684

Optimisation of the Blood Culture Pathway Utilising Behaviour Change

Observational Microbiology Blood Culture

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Microbiology, Blood Culture. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United Kingdom
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Blood culture (BC) is the gold standard for the definitive diagnosis of bacteraemia, providing the opportunity to recover and identify the causative organism, and optimize subsequent antimicrobial treatment. Detection of bacteraemia is critical for the management of sepsis. This study aims to examine the performance of the blood culture pathway in Gloucestershire Hospitals Trust using data analysis, questionnaires and focus groups. . Information collected will be used to design interventions that could be used to optimise the blood culture pathway

Detailed description

Retrospective data collection relating to the blood volume collected and time to incubation of adult blood culture sets (adult sets comprises of both aerobic and anaerobic blood culture bottle) received in the microbiology laboratory, between February 2023 and April 2024. These samples are routinely collected as standard of care and not for the purpose of this research.

Staff members that collect adult blood cultures within the Trust (nurses, Physician's associates and doctors) will be invited to volunteer for the study. Staff members will participate by completing the questionnaire and/or attending focus groups.

Primary outcome measures

  • Compliance to optimal blood culture (BC) vol (8-10 mls per bottle). [Time frame: Retrospective data collection from period February 2023 to April 2024.]
  • Compliance to 4- hour time target to incubation of blood culture from collection. [Time frame: Retrospective data collection from period February 2023 to April 2024]
  • Time from collection of blood cultures to targeted antibiotics, hours and minutes [Time frame: Retrospective data collection from period February 2023 to April 2024.]
  • Staff experiences related to taking blood cultures [Time frame: Approximately 10 minutes to complete electronic questionnaire. Attendance at single FOCUS group at agreed time.]

Eligibility criteria

Inclusion criteria

Secondary data:

\- adult blood culture sets received in the microbiology laboratory, between February 2023 and April 2024.

Staff member participants

\- Staff members that collect adult blood cultures within the Trust

Exclusion criteria

Secondary data:

  • paediatric blood culture samples
  • samples where volume, collection and/or time to incubation data are not recorded on laboratory system and/or blood culture analyser

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Other

Study locations

United Kingdom · 1 center
  • Gloucestershire Royal Hospital — Gloucester

Identifiers

NCT: NCT07392684 · 24/043/GHT

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗