Exercise Therapy for Multiple Myeloma Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Orthopedic consultation and rehabilitation by excercise therapy.
- Who it may be relevant to
- Registry conditions: Multiple Myeloma Bone Lesions. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Germany
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Structural Measures for Multiple Myeloma Patients to Improve Rehabilitation by Exercise Therapy
Overview
Physical exercise is an important supportive therapy for cancer patients, as it improves quality of life in general and might mitigate the side effects of drug treatment. For patients with multiple myeloma in particular, significantly less evidence on the effectiveness of exercise therapy is available due to the fact that this disease is associated with severe bone degradation which might affect bone stability. Advances in oncologic drug treatment have improved overall survival in multiple myeloma significantly. Therefore, there is an increased interest for recommendations on physical activity in this patient group. Due to uncertainties regarding safety and feasibility of exercise therapy in multiple myeloma, both patients and therapists often remain hesitant. Therefore, an orthopaedic outpatient clinic has been established at the Myeloma Center of Heidelberg University Hospital. Here, patients receive consultation on bone stability and individualized physical exercise plans. Based on the expertise gained at the orthopaedic outpatient clinic, the aim of this study is to establish and evaluate structural measures for improved rehabilitation in multiple myeloma and to integrate them into routine clinical care.
Interventions
- Other Orthopedic consultation and rehabilitation by excercise therapy
All patients will receive a continuous orthopaedic consultation on bone stability and recommendations for exercise therapy during the different phases of systemic myeloma therapy. Thereby, structural measures to improve rehabilitation in multiple myeloma will be established and evaluated with the intention of integrating them into routine clinical care.
Primary outcome measures
- Change in physical function [Time frame: From enrollment to the end of induction therapy after 18 weeks]
Eligibility criteria
Inclusion criteria
- newly diagnosed multiple myeloma
- Survival prognosis > 6 months
- ECOG status ≤ 3
- Age ≥18 years
- Patients who state that they want to carry out the training program at least 2 x/week and participate in the planned follow-up visits
- Ability to give informed consent
- Written consent to participate in the study
- Sufficient knowledge of written and spoken German
Exclusion criteria
- physical or mental limitation that would prevent participation in the training program or the planned follow-up visits
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Supportive care
Study locations
Germany · 1 center
- Heidelberg University Hospital - GMMG Study Group — Heidelberg
Identifiers
NCT: NCT07388147 · S-561/2025