Effect of Peer-led Educational Intervention on Treatment Outcomes Among Adults With Drug-susceptible Pulmonary Tuberculosis in South Omo and Ari Zone, Southern Ethiopia

Official title

Effect of Peer-led Educational Intervention on Treatment Outcomes Among Adults With Drug-susceptible Pulmonary Tuberculosis in South Omo and Ari Zone, Southern Ethiopia: A Protocol for a Cluster- Randomized Controlled Trial Study

Overview

The study might come up with valuable findings to address poor treatment outcome, poor quality of life, disability score and depressive symptoms. The findings may also be decreased health professional workload. The findings would be supportive evidences for policy makers, program managers, to clinician as well as the patients themselves and for other researchers. The study may help to promote and maintain good treatment outcome for the patients in the study area as well as the country. The findings will also be used for teaching \& learning purposes in educational \& training programs.

Detailed description

Peer-led education is an effective approach in improving knowledge and attitude. It is also helpful to reach specific marginalized populations, to reduce social stigma and to enhance adherence by improving behavioral outcomes since behaviour is socially influenced and behavioral norms are developed through social interaction. Peers are underused resources for strengthening TB control and prevention because they have a unique power to support socially excluded patients through sharing their personal experience, to affirm previous beliefs and intentions, and to inspire future opportunities. Peers are more preferred than TB focal persons because they act as a friend, as an educator, as an activist, as a role model and as a team member but TB focal persons act only as an educator. So, this manual is organized to improve knowledge and attitude towards tuberculosis, to reduce social stigma and to strengthen TB control and prevention strategies

Interventions

• Combination product peer-led education
  The Intervention is a structured, evidence-based program designed to promote positive and sustained behavioral changes among participants through education, counseling, and supportive follow-up

Primary outcome measures

• treatment success rate [Time frame: the primary outcome will be measured at the end of 6 months i.e after July 24/2026]

Eligibility criteria

Inclusion criteria

• Adults with new drug-susceptible pulmonary TB who will be diagnosed in bacteriological diagnostic methods
• not participating in similar study,
• mentally capable to provide consent,
• physically capable of following the intervention.

Exclusion criteria

• Seriously ill patients at the time of screening or enrollment
• Tuberculosis patients with a known plan to be transferred out of the study sites

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation

N/A

Model

Single group

Masking

Open label

Primary purpose

Treatment

Study locations

Ethiopia · 1 center

• Jinka University — Jinka

Publications

• Authors (full names or at least last name + initials, in order) Article title Journal name Publication date (year, and month if available) Volume number Page numbers

Identifiers

NCT: NCT07387601 · 4064/2024

Primary sources (government registries)

• ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗