Menu
Not yet recruiting NCT07385976

The Role of Blood Perfusion in Cervical Cancer, Cervical Intraepithelial Neoplasm and Ovarian Cancer Patients

— Observational Cervical Cancer Cervical Intraepithelial Neoplasm Ovarian Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Doppler ultrasound.
Who it may be relevant to
Registry conditions: Cervical Cancer, Cervical Intraepithelial Neoplasm, Ovarian Cancer. Basic parameters: No limits · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Taiwan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

This study will elucidate the role of 3D transvaginal ultrasound in assessing (1) cervical vascularity and blood flow in patients with cervical cancer and cervical intraepithelial neoplasm, and (2) tumor vascularity and blood flow in patients with ovarian cancer.

Detailed description

Patients and methods:

Women with cervical cancer, cervical intraepithelial neoplasm, ovarian cancer, or the control will be invited to particilate in this study.Then, 3D power Doppler Ultrasound will be performed to capture (1) the cervical volume, vascularity and blood perfusion, and (2) ovarian tumor vascularity and blood perfusion. The sonographic data will be correlated to clinical and pathological data.

Interventions

  • Diagnostic test Doppler ultrasound
    3D doppler ultrasound to measure VI, FI, VFI.

Primary outcome measures

  • Vascularization-flow index [Time frame: 3 years]
Secondary outcome measures (2)
  • Vascularization index [Time frame: 3 years]
  • Flow index [Time frame: 3 years]

Eligibility criteria

Inclusion criteria

  • Regarding the topic "Hemoperfusion characteristics of cervical cancer and precancerous lesions, and the correlation between hemoperfusion and prognosis":
  • Adult women who have had a normal cervical smear within the past three years and have no other gynecological cancers (control group).
  • Adult women with cervical cancer or precancerous lesions.
  • Regarding the topic "Correlation between hemoperfusion and prognosis of ovarian cancer":
  • Adult women suspected of having ovarian cancer, fallopian tube cancer, or peritoneal cancer before surgery.

Exclusion criteria

  • Regarding the topic "Hemoperfusion characteristics of cervical cancer and precancerous lesions of the cervix, and the correlation between hemoperfusion and prognosis":

1\. Patients who cannot cooperate with vaginal 3D ultrasound scans.

  • Regarding the topic "Correlation between hemoperfusion and prognosis of ovarian cancer":
  • Patients who cannot cooperate with vaginal or abdominal 3D ultrasound scans.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

Taiwan · 2 centers
  • Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, — New Taipei City
  • Far Eastern Memorial Hospital — New Taipei City

Identifiers

NCT: NCT07385976 · 114237-F

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗