In This toGether R01
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Level up quizzes, Badges, On-demand advice, Content.
- Who it may be relevant to
- Registry conditions: HIV. Basic parameters: 18 years — 22 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Uganda
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
In This toGether: Testing a Population-based Text Messaging-based HIV Prevention Program for Young Adults Across Uganda
Overview
The goal of this study is to assess the effectiveness of the text-based ITG intervention to promote behaviors associated with HIV prevention amongst 18-22 year-olds in Uganda. The main questions the study aims to answer are: 1. In a twelve-month period, does the intervention increase HIV testing and use of condoms? a. How do the different interactive elements effect this? 2. How is effectiveness different for populations based on education, sex, and location (urban/rural)? Researchers will compare the control group, with no intervention, and the three combinations of the three intervention components: quiz questions, milestone badges, and access to on-demand advice. Participants will receive the intervention via text messages and partake in the interactive elements listed above.
Interventions
- Other Level up quizzes
Participant is given weekly quiz questions on that week's texted content - Other Badges
Participants can earn badges by performing activities encouraged by program - Other On-demand advice
Participants have access to ITGenie/Text Buddy, which responds to keywords with preset messages - Other Content
Texted information about HIV prevention
Primary outcome measures
- HIV testing [Time frame: 12 months]
- Condom-protected sex acts [Time frame: 12 months]
Eligibility criteria
Inclusion criteria
- Live in Uganda
- Age 18 to 22
- Have exclusive ownership of a cell phone
- Have used text messaging for at least 6 months
- Able to read English, Luganda, Runyakitara, or Luo
Exclusion criteria
- Not participated in preliminary R34 study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Factorial
- Masking
- Single blind
- Primary purpose
- Prevention
Study locations
Uganda · 1 center
- Internet Solutions for Kids Uganda — Mbarara
Publications
- Collins LM, Kugler KC, Gwadz MV. Optimization of Multicomponent Behavioral and Biobehavioral Interventions for the Prevention and Treatment of HIV/AIDS. AIDS Behav. 2016 Jan;20 Suppl 1(0 1):S197-214. doi: 10.1007/s10461-015-1145-4. PMID 26238037
- Ybarra ML, Agaba E, Nyemara N. A Pilot RCT Evaluating InThistoGether, an mHealth HIV Prevention Program for Ugandan Youth. AIDS Behav. 2021 Oct;25(10):3437-3448. doi: 10.1007/s10461-021-03237-5. Epub 2021 May 7. PMID 33963477
- Matovu J, Wanynze R, Kasozi D. Assessment of the implementation processes and outcomes of the HIV assisted partner notification program in Uganda. Kampala: Makerere University School of Public Health. Published online July 2021.
- Bogart LM, Musoke W, Mukama CS, Allupo S, Klein DJ, Sejjemba A, Mwima S, Kadama H, Mulebeke R, Pandey R, Wagner Z, Mukasa B, Wanyenze RK. Enhanced Oral Pre-exposure Prophylaxis (PrEP) Implementation for Ugandan Fisherfolk: Pilot Intervention Outcomes. AIDS Behav. 2024 Oct;28(10):3512-3524. doi: 10.1007/s10461-024-04432-w. Epub 2024 Jul 19. PMID 39028385
Identifiers
NCT: NCT07382765 · R01MH136955 · R01MH136955