geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Genicular Artery Embolization.
- Who it may be relevant to
- Registry conditions: Knee Osteoarthristis. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Creation Of a Prospective Registry For Genicular Artery Embolization At The Joint & Vascular Institute
Overview
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The main questions it aims to answer are: 1. Does GAE lead to sustained improvement in pain (WOMAC, VAS) and quality-of-life scores over 12-36 months? 2. What patient or procedural factors are associated with better outcomes after GAE? Participants will: * Undergo GAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.
Interventions
- Procedure Genicular Artery Embolization
Genicular Artery Embolization (GAE) is a minimally invasive, image-guided procedure in which embolic agents are delivered into hyperemic genicular arteries to reduce synovial inflammation and knee pain from osteoarthritis.
Primary outcome measures
- Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) [Time frame: 5 years of enrollment/patient]
Eligibility criteria
Inclusion criteria
- Adults (≥18 years) with symptomatic KOA refractory to medical therapy, referred for GAE.
Exclusion criteria
- Pregnancy, coagulopathy, severe comorbidities, or inability to consent.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Joint and Vascular Institute — Libertyville
Identifiers
NCT: NCT07380906 · 1396188