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Recruiting NCT07378956

Clinical Efficacy of Implementing an AI-SaMD for Funduscopy Analysis in Patients With Diabetes Mellitus

No phase Interventional Diabetic Retinopathy (DR) Diabete Mellitus Fundus Photography

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: VUNO Med®-Fundus AI™.
Who it may be relevant to
Registry conditions: Diabetic Retinopathy (DR), Diabete Mellitus, Fundus Photography. Basic parameters: from 19 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
South Korea
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Clinical Efficacy of Implementing an AI-Driven Software as a Medical Device (SaMD) for Funduscopy Analysis in Patients With Diabetes Mellitus: A Randomized Controlled Trial Protocol

Overview

The objective of this study is to investigate the efficacy of implementing the AI-SaMD(VUNO Med®-Fundus AI™) alongside routine clinical practice for the detection of diabetic retinopathy.

Detailed description

The primary objective of this study is to compare the true referral rate between patients with VUNO Med®-Fundus AI™-assisted screening (intervention group) and those receiving usual clinical care without AI assistance (control group) among patients with diabetes mellitus.

Interventions

  • Device VUNO Med®-Fundus AI™
    VUNO Med®-Fundus AI™ is an artificial intelligence-based fundus image detection and diagnostic support software. The software automatically identifies abnormal retinal findings and provides information on the type and location of detected abnormalities to aid clinical decision-making.

Primary outcome measures

  • True Referral Rate [Time frame: within 6 months]
Secondary outcome measures (7)
  • Diabetic Retinopathy (DR) Diagnosis Rate [Time frame: Within 6 months]
  • Odds Ratio [Time frame: Within 6 months]
  • Referral Rate [Time frame: Within 6 months]
  • Time to Diabetic Retinopathy Diagnosis [Time frame: Within 6 months]
  • Performance of the AI System in Detecting Diabetic Retinopathy [Time frame: Within 6 months]
  • Accuracy of Referral for Diabetic Retinopathy [Time frame: Within 6 months]
  • Adherence Rate [Time frame: Within 6 months]

Eligibility criteria

Inclusion criteria

  • Adults aged 19 years or older.
  • A documented diagnosis of type 2 diabetes mellitus.
  • Ability to communicate adequately and provide written informed consent for participation in the study.

Exclusion criteria

  • A prior diagnosis of diabetic retinopathy at the time of screening.
  • A history of ophthalmic surgery within 6 months prior to the screening date.
  • A diagnosis of type 1 diabetes mellitus.
  • Pregnancy at the time of screening.
  • Any condition that, in the opinion of the investigator, would make participation in the study infeasible or inappropriate.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Screening

Study locations

South Korea · 1 center
  • Inha University Hospital — Incheon

Identifiers

NCT: NCT07378956 · VN-M-03 PR

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗