Recruiting NCT07376915
Acute Effect of Graded Motor Imagery on Ankle Rehabilitation: A Pilot Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: graded motor imagery.
- Who it may be relevant to
- Registry conditions: Ankle Instability, Healthy Controls. Basic parameters: 18 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Acute Effect of Graded Motor Imagery-Based Mental Preparation on Ankle Rehabilitation: A Pilot Clinical Study
Overview
The primary aim of this study is to evaluate the immediate and short-term effects of the Graded Motor Imagery (GMI) method on individuals with chronic ankle instability (CAI). In this context, the effects of the Graded Motor Imagery intervention on pain level, muscle stiffness, muscle strength, functional performance, and subjective instability level will be investigated. Additionally, these effects will be comparatively analyzed with an age- and sex-matched control group consisting of healthy individuals.
Interventions
- Other graded motor imagery
The Graded Motor Imagery (GMI) program will be applied six consecutive days nd will consist of three progressive stages: Laterality Training: Participants will perform right-left ankle discrimination tasks using validated foot and ankle images. Accuracy and response time will be recorded. Motor Imagery: Participants will mentally rehearse ankle movements such as dorsiflexion, plantarflexion, inversion, and eversion without performing the motion. Imagery tasks will progress from simple moveme
Primary outcome measures
- Subjective Instability (CAIT) [Time frame: baseline]
- Subjective Instability (CAIT) [Time frame: 1-week post-intervention]
- Ground Reaction Force & Static Balance (ForceDecks) [Time frame: baseline]
- Ground Reaction Force & Static Balance (ForceDecks) [Time frame: 1-week post-intervention]
Secondary outcome measures (8)
- Muscle Stiffness (Myoton PRO) [Time frame: baseline]
- Muscle Stiffness (Myoton PRO) [Time frame: 1-week post-intervention]
- Muscle Strength Assessment - Isokinetic dynamometer (Isoforce) [Time frame: baseline]
- Muscle Strength Assessment - Isokinetic dynamometer (Isoforce) [Time frame: 1-week post-intervention]
- Pain Level [Time frame: baseline]
- Pain Level [Time frame: 1-week post-intervention]
- Functional Performance [Time frame: baseline]
- Functional Performance [Time frame: 1-week post-intervention]
Eligibility criteria
Inclusion criteria
- Aged between 18 and 40 years.
- Diagnosed with chronic ankle instability (CAIT ≤ 24).
- History of an acute ankle sprain occurring more than 3 months prior to enrollment.
- Has not received ankle rehabilitation treatment.
- Voluntarily participated in this study
Exclusion criteria
- Vestibular or neurological disorders
- Other lower extremity injuries
- History of surgery
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Non-randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Supportive care
Study locations
Turkey (Türkiye) · 1 center
- İstanbul Üniversitesi-Cerrahpaşa — Istanbul
Publications
- Kim KM, Estepa-Gallego A, Estudillo-Martinez MD, Castellote-Caballero Y, Cruz-Diaz D. Comparative Effects of Neuromuscular- and Strength-Training Protocols on Pathomechanical, Sensory-Perceptual, and Motor-Behavioral Impairments in Patients with Chronic Ankle Instability: Randomized Controlled Trial. Healthcare (Basel). 2022 Jul 22;10(8):1364. doi: 10.3390/healthcare10081364. PMID 35893186
- Naderi A, Ahi K. Comparative analysis of land-based vs. water-based balance training on quality of life and physical and psychological deficits in athletes with chronic ankle instability: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2025 Jan 20;17(1):9. doi: 10.1186/s13102-024-01049-3. PMID 39828772
- David P, Halimi M, Mora I, Doutrellot PL, Petitjean M. Isokinetic testing of evertor and invertor muscles in patients with chronic ankle instability. J Appl Biomech. 2013 Dec;29(6):696-704. doi: 10.1123/jab.29.6.696. Epub 2013 Jan 18. PMID 23343782
- Wright CJ, Linens SW, Cain MS. Establishing the Minimal Clinical Important Difference and Minimal Detectable Change for the Cumberland Ankle Instability Tool. Arch Phys Med Rehabil. 2017 Sep;98(9):1806-1811. doi: 10.1016/j.apmr.2017.01.003. Epub 2017 Jan 27. PMID 28137476
- Moseley GL. Graded motor imagery for pathologic pain: a randomized controlled trial. Neurology. 2006 Dec 26;67(12):2129-34. doi: 10.1212/01.wnl.0000249112.56935.32. Epub 2006 Nov 2. PMID 17082465
Identifiers
NCT: NCT07376915 · 2025/377