Effects of Acute Sugar Intake on Choroidal Thickness
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Oral glucose.
- Who it may be relevant to
- Registry conditions: Choroid. Basic parameters: 21 years — 35 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
This study aims to bridge that gap by investigating how acute sugar intake influences choroidal thickness.
Detailed description
This investigation will be a prospective, repeated-measures study. All subjects will arrive fasted and will be asked not to consume any outside food or beverages during the three-hour study period, and will be asked to abstain from caffeine intake for 12 hours before participation. A baseline OCT scan of the macula of the right eye will be performed using the Heidelberg Spectralis OCT system. Participants will then consume 30 grams of sugar in the form of glucose tablets. Macular OCT scans of the right eye will be repeated every 30 minutes for 3 hours following sugar consumption.
Interventions
- Dietary supplement Oral glucose
Participants will consume 30 grams of sugar in the form of glucose tablets.
Primary outcome measures
- Change in choroidal thickness [Time frame: within 3 hours of baseline]
Eligibility criteria
Inclusion criteria
- In order to be eligible for enrolment, each subject must have less than 6 diopters of spherical equivalent refractive error, and have no existing diagnosis of diabetes or pre-diabetes.
Exclusion criteria
- Any potential subject with known retinal pathology will be excluded. Any potential subject with any other known systemic or ocular conditions that may impact their ability to participate in the study or provide generalizable data will also be excluded.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Other
Study locations
United States · 1 center
- Southern College of Optometry — Memphis
Identifiers
NCT: NCT07376005 · 2025-12-01PS