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Recruiting NCT07369427

Magnetic Tracking and ECG-Guided Tip Confirmation System for PICCs

Observational Peripherally Inserted Central Catheters

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Sherlock 3CG Tip Confirmation System.
Who it may be relevant to
Registry conditions: Peripherally Inserted Central Catheters. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Magnetic Tracking and Electrocardiography-Guided Tip Confirmation System for Placement of Peripherally Inserted Central Catheters

Overview

This prospective study enrolled cancer patients who underwent peripherally inserted central catheter (PICC) placement at a tertiary care oncology hospital in Guangzhou between January 1st and May 30th, 2026. Data on catheterization outcomes and complications were collected to compare two tip positioning techniques: electromagnetic navigation tip positioning and traditional electrocardiogram (ECG)-guided positioning. The outcomes assessed included first-attempt catheterization success rate, tip positioning accuracy, catheterization procedure time, post-procedural catheter adjustment time, and the incidence of complications (thrombosis, infection, and catheter dysfunction) within 4 weeks post-catheterization.

Interventions

  • Other Sherlock 3CG Tip Confirmation System
    Sherlock 3CG Tip Confirmation System: An integrated system combining magnetic navigation tracking and ECG guidance. It dynamically confirms the tip's position relative to the target anatomical location (e.g., superior vena cava-right atrial junction) by real-time tracking of the catheter tip's spatial position via magnetic navigation and synchronously monitoring ECG signals (e.g., P-wave changes). Traditional ECG-Guided Tip Positioning Technology: Relying solely on ECG monitoring for guidance,

Primary outcome measures

  • one time catheterization rate [Time frame: data will be collected on Day 1]
Secondary outcome measures (4)
  • time for catheter tip positioning during catheterization [Time frame: on Day 1]
  • time for catheter tip adjustment after catheterization [Time frame: on Day 1]
  • rate of correct catheter tip positioning [Time frame: on Day 1]
  • rate of PICC-related complications [Time frame: within 4 weeks after catheterization]

Eligibility criteria

Inclusion criteria

  • cancer patients receiving PICC placement
  • High risk of PICC-related thrombosis(Evaluated by Caprini score ≥ 5)
  • Agree to receive PICC maintenance at the research hospital;
  • Sign the informed consent form

Exclusion criteria

  • PICC placed in the lower limb
  • Estimated survival time less than one month

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Sun Yat-sen University Cancer Center — Guangzhou

Identifiers

NCT: NCT07369427 · SunYat-senU6

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗