Clinical and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride, With or Without Application of LED, in Arresting Incipient Permament Molar Caries
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: International Sliver Diamine Fluoride, Local brand Egyptian Silver Diamine Fluoride, Silver Fluoride, International Sliver Diamine Fluoride with LED light.
- Who it may be relevant to
- Registry conditions: Incipient Caries. Basic parameters: 18 years — 25 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Clinical Efficacy and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride to Arrest Incipient Carious Lesions in Permanent Molar Teeth With or Without Application of LED Light: A Randomized Clinical Trial
Overview
The study aims to compare the effect of international brand ammonia based 38% SDF, water based silver fluoride solution (AgF), an aqueous silver fluoride solution, and local brand ammonia based SDF with and without LED light application on caries arrest of initial enamel pits and fissure caries for permanent teeth of young adults
Interventions
- Other International Sliver Diamine Fluoride
It is the gold standard; it is an international brand, it is ammonia-based, and it is a remineralizing agent with an application time of 60 seconds. - Other Local brand Egyptian Silver Diamine Fluoride
It is a new Egyptian brand of SDF; it is ammonia-based, and it is a remineralizing agent with an application time of 60 seconds. - Other Silver Fluoride
It is a water-based remineralizing agent with an application time of 60 seconds. - Other International Sliver Diamine Fluoride with LED light
It is an international brand, it is ammonia-based, and it is a remineralizing agent with an application time of 10 seconds, followed by LED light application for 20 seconds. - Other Local brand Egyptian Silver Diamine Fluoride with LED light
It is a new Egyptian brand of SDF; it is ammonia-based, and it is a remineralizing agent with an application time of 10 seconds, followed by LED application for 20 seconds. - Other Silver Fluoride with LED light
It is a water-based remineralizing agent with an application time of 10 seconds, followed by LED light application for 20 seconds.
Primary outcome measures
- Caries arrest [Time frame: After 3, 6, and 12 months.]
Eligibility criteria
Inclusion criteria
- high caries risk dental students
- Males or females
- Medically free
- Not taking medication
- At least had one active carious tooth
- Posterior permanent teeth
- ICDAS 2
Exclusion criteria
- non-Egyptian students
- Lack of compliance
- Allergic reaction to the materials used
- Pregnancy
- Dental students cannot give consent
- Teeth that will be extracted for orthodontic reasons
- Dental fluorosis
- Hypo calcified teeth
- Systemic diseases affecting teeth, such as amelogenesis imperfecta
- Severe periodontal affection
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Prevention
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07366645 · 3344515