Prolonged Extubation in Gastric Cancer With OSA
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Prolonging the duration of postoperative endotracheal intubation before extubation..
- Who it may be relevant to
- Registry conditions: Obstructive Sleep Apnea, Gastric Cancer (GC). Basic parameters: 18 years — 85 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
An Exploratory Study on the Impact of Prolonged Postoperative Endotracheal Extubation Time on Postoperative Complications in Gastric Cancer Patients With Severe Obstructive Sleep Apnea
Overview
This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
Detailed description
This study retrospectively included patients who underwent radical gastrectomycombined with severe obstructive sleep apnea at Qilu Hospital . Accordingto the assessment of anesthesiologists, whether the anesthetic drugs of the patients were adequatelymetabolized during the operation. The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
Interventions
- Procedure Prolonging the duration of postoperative endotracheal intubation before extubation.
The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
Primary outcome measures
- Postoperative complications [Time frame: 48-72 hour]
Eligibility criteria
Inclusion criteria
- Patients preoperatively diagnosed with resectable gastric cancer
- Patients without distant organ metastasis
- Patients with preoperative Overnight Cardiorespiratory Sleep Testing (OCST) or Polysomnography (PSG) results showing Apnea-Hypopnea Index (AHI) >30 events/hour and SaO₂ <80%
- Patients with cardiopulmonary function deemed suitable for surgery
- Patients aged 18-85 years
- Patients who voluntarily joined this study and provided written informed consent
Exclusion criteria
- Patients with a history of or concurrent other malignant tumors
- Patients who underwent palliative resection
- Subjects who experienced acute cardiovascular or cerebrovascular events (e.g., acute cerebral infarction, acute coronary syndrome) within the past 3 months, or whose cardiovascular clinical symptoms/diseases are not well-controlled
- Patients with a history of psychotropic drug abuse that cannot be abstained, or those with psychiatric disorders
- Patients with concomitant diseases that, in the investigator's judgment, seriously endanger the patient's safety or affect the completion of the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Qilu Hospital of Shandong University — Jinan
Identifiers
NCT: NCT07362706 · KYLL-202110-034-2