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Not yet recruiting NCT07361978

The Effect of Pursed-Lip Breathing Exercise on Anxiety and Physiological Parameters Post-Bronchoscopy in Patients With COPD: A Randomized Controlled Trial

No phase Interventional COPD

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Pursed-Lip Breathing exercise and Routine Care.
Who it may be relevant to
Registry conditions: COPD. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Effect of Purse-Lip Breathing Exercise on Anxiety and Physiological Parameters Post-Bronchoscopy in Patients With COPD: A Randomized Controlled Trial

Overview

This randomized controlled trial investigates the effect of Pursed Lip Breathing (PLB) on anxiety levels and physiological parameters in patients with Chronic Obstructive Pulmonary Disease (COPD) following bronchoscopy. While PLB is known to improve oxygenation and ventilation in pulmonary rehabilitation, its specific impact on the immediate recovery period after bronchoscopy is understudied. The study aims to determine if nurse-led PLB intervention significantly improves heart rate, blood pressure, oxygen saturation, and reduces anxiety compared to standard care.

Detailed description

Chronic Obstructive Pulmonary Disease (COPD), which ranks among the leading causes of morbidity and mortality worldwide, is expected to have increasingly negative consequences. There are over 600 million COPD patients worldwide and approximately 2-3 million in Turkey. COPD requires a complex and long-term response that coordinates the contributions of a wide range of professionals, specific types of medication, and appropriate monitoring equipment, and this care should ideally be integrated into a system that promotes patient empowerment. The associated treatment process involves repeated hospital admissions, which impose high economic costs on countries.

In the dynamic environment of critical care medicine, bedside bronchoscopy has emerged as a crucial diagnostic and therapeutic tool that bridges the gap between traditional pulmonary interventions and the urgent needs of critically ill patients. Bronchoscopy allows direct visualization of the airways and lung parenchyma and can be useful in evaluating various bronchopulmonary conditions and diseases, including foreign bodies, tumors, infectious and inflammatory processes, airway obstruction, and bronchopulmonary hemorrhage. Bronchoscopy may also be associated with other complications and discomforts beyond existing respiratory system problems.

Teaching patients breathing exercises is another nursing intervention that can increase oxygenation and reduce dyspnea. Various breathing exercises are available, including PLB. PLB is a breathing technique used to improve oxygenation and ventilation. This breathing technique involves consciously inhaling through the nose, followed by a slow and controlled exhalation through pursed or pinched lips, which prolongs the exhalation phase compared to the normal inspiration-exhalation ratio.

Nurses' ability to promptly recognize distress enables intervention teams to respond quickly and prevent further deterioration. The literature shows that pursed-lip breathing improves vital signs and oxygenation in COPD rehabilitation and during the recovery process after bronchoscopy. In a recent study, patients who practiced pursed-lip breathing during the post-bronchoscopy period showed significant improvements in parameters such as oxygen saturation, pulse rate, and blood pressure compared to the control group. However, studies examining the effect of this technique on anxiety and immediate physiological parameters in COPD patients during the bronchoscopy procedure are limited. This study was designed as a randomized controlled trial to determine the effect of PLB application on anxiety levels and physiological parameters (heart rate, blood pressure, oxygen saturation) in patients with COPD after bronchoscopy.

Interventions

  • Other Pursed-Lip Breathing exercise and Routine Care
    Pursed-Lip Breathing exercise will be done. Following a conscious inhalation through the nose, it involves exhaling slowly and in a controlled manner through pursed lips; this prolongs the exhalation phase compared to the normal inspiration-exhalation ratio.

Primary outcome measures

  • Change in State Anxiety Level [Time frame: Baseline (Pre-procedure) and immediately after the bronchoscopy procedure (up to 30 minutes).]
Secondary outcome measures (4)
  • Change in Oxygen Saturation (SpO2) [Time frame: Baseline, during the procedure, and immediately after the procedure. Baseline, during the procedure, and immediately after the procedure. (30 minutes before and after the procedure.)]
  • Change in Heart Rate [Time frame: Baseline, during the procedure, and immediately after the procedure (up to 30 minutes).]
  • Change in Systolic Blood Pressure [Time frame: Baseline (pre-procedure), during the procedure, and immediately after the procedure (up to 30 minutes).]
  • Change in Diastolic Blood Pressure [Time frame: Baseline (pre-procedure), during the procedure, and immediately after the procedure (up to 30 minutes).]

Eligibility criteria

Inclusion criteria

  • Patients diagnosed with COPD
  • Patients undergoing elective bronchoscopy under sedation
  • Patients aged 18 - 80 years
  • Patients who are fully oriented, conscious, and able to communicate

Exclusion criteria

  • Patients undergoing emergency bronchoscopy
  • Patients with hemodynamic instability prior to the procedure (systolic blood pressure <90 mmHg or >180 mmHg)
  • Patients with severe hearing or cognitive impairment

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Screening

Study locations

Turkey (Türkiye) · 1 center
  • Süreyyapaşa Göğüs Hastalıkları ve Göğüs Cerrahisi EAH — Istanbul

Identifiers

NCT: NCT07361978 · 133.2025fbu

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗