Delivery Mode Impact on Postoperative Depression
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Postoperative Depression. Basic parameters: from 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Impact of Elective Versus Emergency Cesarean Delivery on Early Postpartum Depression: a Retrospective Study
Overview
The goal of this observational retrospective cohort study is to examine the association between mode of delivery and early postpartum depressive symptoms in adult women who delivered at Massachusetts General Hospital. Specifically, the study evaluates whether the urgency of cesarean delivery (elective versus emergency) is associated with differences in Edinburgh Postnatal Depression Scale (EPDS) scores at 6-8 weeks postpartum, compared with elective cesarean delivery and vaginal delivery. The EPDS is a validated 10-item self-report questionnaire with scores ranging from 0 to 30, where higher scores indicate more severe depressive symptoms. The primary questions are whether EPDS scores differ among women undergoing emergency cesarean delivery, elective cesarean delivery, and vaginal delivery, and whether perioperative and obstetric factors are associated with postpartum depressive symptoms. This study involves retrospective analysis of de-identified electronic health record data. Participants will not undergo any study-specific interventions.
Primary outcome measures
- Edinburgh Postnatal Depression Scale (EPDS) scores, a 10-item self-reported screening tool for postpartum depression (range: 0-30, with higher scores indicating more severe depressive symptoms) [Time frame: 6-8 weeks postpartum]
Secondary outcome measures (1)
- Prevalence of postpartum depression [Time frame: 6-8weeks]
Eligibility criteria
Inclusion criteria
Underwent cesarean delivery (elective or emergency) or vaginal delivery during the study period
Age 18 years or older
Completed at least one Edinburgh Postnatal Depression Scale (EPDS) assessment at 6-8 weeks postpartum
Have complete perioperative data available
Exclusion criteria
Missing 6-8 week postpartum EPDS scores
Pregnancy with fetal demise, severe obstetric complications, or atypical maternal conditions
History of severe psychiatric disorders (e.g., schizophrenia, bipolar disorder), when identifiable
Incomplete perioperative medical records
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07359170 · 2025P002461