Physical Acvitiy in Pregnancy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Pregnancy Physical Activity Questionnaire (PPAQ).
- Who it may be relevant to
- Registry conditions: Pregnant Women, Gestational Diabetes, Obese But Otherwise Healthy Participants, Overweight (BMI > 25). Basic parameters: 18 years — 45 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Epigenetic Regulation of Physically Active Lifestyle on Placental Development
Overview
The goal of this observational study is to learn how a physically active lifestyle during pregnancy affects placental development and function. The main question it aims to answer is: Does regular physical activity during pregnancy improve placental function and support healthy fetal growth? Pregnant participants will provide biological samples and health information during pregnancy and at delivery. The study will use these samples to examine how activity levels relate to placental energy production and overall health.
Detailed description
This observational study aims to examine how a physically active lifestyle during pregnancy affects placental function and fetal development. We will enroll pregnant participants and collect biological samples, including blood and placental tissue after delivery. The study will measure markers of placental energy production and other indicators of placental health to understand the mechanisms by which maternal physical activity may influence fetal growth.
Data collected will also include health information, lifestyle questionnaires, and activity assessments during pregnancy. Participants will not need to change their normal exercise habits. The results of this study may help identify how maternal physical activity supports placental and fetal health, which could inform future recommendations for healthy pregnancies.
Interventions
- Behavioral Pregnancy Physical Activity Questionnaire (PPAQ)
The PPAQ is a semiquantitative questionnaire that asks respondents to report the time spent participating in 32 activities including household/caregiving (13 activities),occupational (5 activities), sports/exercise (8 activities), transportation (3 activities), and inactivity (3 activities). For each activity, respondents are asked to select the category that best approximates the amount of time spent in that activity per day or week during the currenttrimester. Possible durations range from 0
Primary outcome measures
- Placental mitochondrial function [Time frame: At delivery]
Eligibility criteria
Inclusion criteria
- Pregnant female and their newborn infant(s)
- Aged 18-45 (pregnant female), age 0-60 days of life (newborn infant)
- English speaking
- Screened for gestational diabetes with standard glucose tolerance test between 24w - 41w gestation
- Delivered at gestational age 34week-41weeks
- Delivered via non-emergent Cesarean section during weekday hours
- No known infectious disease (ex: HIV, HepC)
Exclusion criteria
- Women <18yo or >45yo
- Non-English speaking
- Pre-existing diabetes or diagnosed with diabetes prior to 24weeks
- Required complex diets/supplements not related to the pregnancy (i.e. malnutrition)
- Known severe fetal anomalies or genetic disorder
- Placenta accreta spectrum
- Emergent cesarean delivery performed due to fetal distress
- Known infectious disease (ex: HIV, HepC)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- University of Maryland Medical System — Baltimore
Identifiers
NCT: NCT07356180 · HP-00099879