Recruiting NCT07354048

Impact Of Thyroid Dysfunction on Liver Function Tests

— Observational Thyroid Disease

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied: The protocol lists: Control group, Patients with hypothyroidism or hyperthyroidism that are controlled on treatment, Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment, Patients with hypothyroidism or hyperthyroidism that are firstly discovered.
Who it may be relevant to: Registry conditions: Thyroid Disease. Basic parameters: 20 years — 60 years · All.
What needs checking: Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place: Egypt
Next step: Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Official title

Impact Of Thyroid Dysfunction on Liver Function Tests In Sohag University Hospital

This study aims to evaluate the effect of thyroid dysfunction on liver function tests.

Other Control group
Healthy people
Other Patients with hypothyroidism or hyperthyroidism that are controlled on treatment
This group includes patients with hypothyroidism or hyperthyroidism that are controlled on treatment
Other Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment
This group includes patients with hypothyroidism or hyperthyroidism that are not controlled on treatment
Other Patients with hypothyroidism or hyperthyroidism that are firstly discovered
This group includes patients with hypothyroidism or hyperthyroidism that are firstly discovered

Measuring total bilirubin level in patients with thyroid dysfunction diseases [Time frame: 1 months]

All patients between the ages of 20-60 years old either with Hypothyroidism or Hyperthyroidism (controlled on treatment or not) and firstly diagnosed Hypothyroidism or Hyperthyroidism.
Euthyroid controls (clinically healthy control subjects were recruited from the general population with the same socio-economic status with the subjects.)

Patients aged < 20 years old.
Patients With Liver Disease.
Pregnant and lactating women.
Patients with severe infections or sepsis.
Patients with Heart Disease.
Patients who on drugs that can affect liver function such as phenothiazine, phenylbutazone, methyldopa, among others.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Egypt · 1 center

Boelaert K, Franklyn JA. Thyroid hormone in health and disease. J Endocrinol. 2005 Oct;187(1):1-15. doi: 10.1677/joe.1.06131. PMID 16214936
Malik R, Hodgson H. The relationship between the thyroid gland and the liver. QJM. 2002 Sep;95(9):559-69. doi: 10.1093/qjmed/95.9.559. PMID 12205333
Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002 Feb;23(1):38-89. doi: 10.1210/edrv.23.1.0455. PMID 11844744

NCT: NCT07354048 · Soh-Med--25-7-9MS