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Recruiting NCT07351253

Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block for Open Abendectomy Surgery

No phase Interventional Appendicectomy Postoperative Analgesia Regional Anaesthesia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Erector Spinae Plane Block, Transversus abdominis plane (TAP) block.
Who it may be relevant to
Registry conditions: Appendicectomy, Postoperative Analgesia, Regional Anaesthesia. Basic parameters: from 21 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Analgeisc Effect of Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block in Patients Undergoing Open Abendectomy Surgery: a Randomized Controlled Trial

Overview

this aim of this study is to compare the analgesic effect of Erector spinae plane (ESP) block and lateral transversus abdominis plan (TAP) block in patients undergoing open appendectomy.

Detailed description

regional technique according to randomization will be given after induction of general anesthesia Fentanyl boluses of 1 mcg/kg will be given in case of inadequate analgesia. Inadequate analgesia identified by 20% increase in the heart rate and/or systolic blood pressure from baseline measurement.

postoperative analgesia: regular paracetamol 1 g/6 hours (intravenously at first then orally once the oral feeding is resumed) and 75 mg diclofenac (intramuscularly at first then orally once the oral feeding is resumed).

If Numeric rating scale (NRS) is \> 3 intravenous titration of 2 mg morphine is given slowly to be repeated after 30 minutes if pain persisted

Interventions

  • Other Erector Spinae Plane Block
    Patients will receive the ESP block at the level of the 10th thoracic (T10) transverse process using a linear 6-13 MHz ultrasound transducer. A 20 mL of 0.25% bupivacaine will be injected below the muscle
  • Other Transversus abdominis plane (TAP) block
    Patient will received TAP block using the lateral approach while in supine position. A 20 mL of 0.25% bupivacaine will be injected after negative aspiration.

Primary outcome measures

  • Total morphine consumption [Time frame: from extubation until 24 hours postoperative]
Secondary outcome measures (2)
  • numeric rating scale [Time frame: AT 0.5, 2, 6, 12, and 24 hours postoperative.]
  • quality of recovery [Time frame: 24 hours after suregry]

Eligibility criteria

Inclusion criteria

  • adult patients, undergoing open appendectomy.

Exclusion criteria

  • American society of anesthesiologist-physical status >III,
  • allergy to any of the study drugs,
  • coagulopathy
  • local infection,
  • history of chronic pain or regular opioid use;
  • inability to comprehend the Numeric Rating Scale (NRS),
  • pregnant or lactating women.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Triple blind
Primary purpose
Prevention

Study locations

Egypt · 1 center
  • Cairo University — Cairo

Identifiers

NCT: NCT07351253 · MD-320-2024

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗