Digital Interventions for Relapse Prevention in Adolescence
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Transdiagnostic app intervention, Transdiagnostic mastery course.
- Who it may be relevant to
- Registry conditions: Major Depression Disorder, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses). Basic parameters: 16 years — 19 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Norway
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Some adolescents experience periods of anxiety and/or depression, and some find that these periods return over time. The purpose of this study is to examine whether digital interventions-where individuals work systematically with their own thoughts and feelings during periods when they feel well-can help them maintain well-being for longer. The study includes adolescents aged 16-19 who have previously experienced episodes of depression and/or anxiety to a degree that led them to seek help (e.g., from a school nurse, general practitioner, health clinic, or child and adolescent mental health service). Through a research app on their smartphones, participants complete tasks and answer questionnaires. The study is fully digital. Some participants meet with a therapist in digital group sessions, while others work independently with the digital content. We will also examine the cost-benefit aspects of offering such interventions. If the study achieves its goals, digital interventions may eventually become a service offered to adolescents recovering from depression and anxiety.
Interventions
- Behavioral Transdiagnostic app intervention
A transdiagnostic, self-guided CBT app, called TankeVirus (literally translated Thought Viruses), consisting of three components: 1. Standardized self-assessment for mental health: 'Test your psychological immune system'. 2. Educational mini-series: A 30-minute, entertaining video series that teaches users to build resilience by addressing essential needs like sleep (psychological immune system), recognizing negative thought patterns (thought viruses), and developing healthier coping mechanisms - Behavioral Transdiagnostic mastery course
Group-based webinar offering psychoeducation based on principles of CBT.
Primary outcome measures
- Relapse: Number of participants scoring above the diagnostic cut-off on the PHQ-9 modified for teens during the 12-month follow-up. [Time frame: From enrollment to the end of follow-up at 12-months.]
- Time until relapse; reaching the diagnostic criteria of MDD according to PHQ-9 modified for teens [Time frame: From enrollment to 12-months follow-up]
Secondary outcome measures (5)
- Repetitive negative thinking (RNT-10) [Time frame: At enrollment, and at 3, 6 and 12 months follow-up]
- Somatic complaints (SSS8) [Time frame: At enrollment, and at 3, 6, and 12-months follow-up.]
- EPOCH Measure of Adolescent Well-Being [Time frame: At baseline, 3, 6 and 12-months follow-up.]
- Health related quality of life [Time frame: At baseline, 3, 6 and 12-months follow-up.]
- Health related quality of life - Visual Analog Scale [Time frame: At baseline, 3, 6 and 12-months follow-up.]
Eligibility criteria
Inclusion criteria
- Currently in full or partial remission for a minimum of 2 months from a depressive disorder or an anxiety disorder as defined by self-reported scores on RCADS-47: previous episode(s) of t-score > 65 and current t-score =<65.
- Native or fluent Scandinavian language skills.
- Willingness to take part even when allocated to the non-preferred arm of the trial.
Exclusion criteria
- Ongoing depressive disorder, ongoing anxiety disorder as defined by current t-score =<65 on RCADS-47.
- Recent completion of one of the interventions in the two interventional arms.
- no available smartphone.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Prevention
Study locations
Norway · 1 center
- University of Oslo — Oslo
Identifiers
NCT: NCT07346911 · 870757