Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Relationship-use questionnaire.
- Who it may be relevant to
- Registry conditions: Borderline Personality Disorder, Borderline Personality Disorder (BPD), Bipolar Disorder (BD). Basic parameters: 18 years — 45 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction to interpersonal relationships. The study builds upon previous findings suggesting that individuals with BPD experience intense emotional dysregulation, including negative self-perception, shame, and a compulsive need for external validation. This addiction to relationships, much like substance use disorders, is thought to contribute significantly to the difficulties faced by these individuals, including interpersonal conflicts, self-destructive behaviors, and emotional instability. The study seeks to demonstrate that the relational difficulties central to BPD meet the diagnostic criteria for addiction as defined by the DSM-5. It will also explore how these relational struggles are mediated by dysfunctional self-perception and whether they are linked to behaviors such as compulsive sexual behaviors (CSBD) or suicidal tendencies. Additionally, the research will investigate the relationship between addiction to relationships and neurobiological factors, including endorphin levels, in individuals with BPD compared to those with bipolar disorder and healthy controls. The hypothesis is that individuals with BPD will exhibit higher levels of relationship addiction, with this addiction being tied to their perception of self-worth and emotional experiences in relationships. This innovative approach aims to refine the understanding of BPD, reduce stigma, and improve treatment strategies by providing scientific evidence supporting the conceptualization of BPD as a "Relationship Use Disorder."
Interventions
- Other Relationship-use questionnaire
Questionnaire adapted from the 'Substance Use Disorders' section of the DSM-5: Disorder related to the use of close relationships
Primary outcome measures
- Relational Addiction [Time frame: Measured at baseline]
Secondary outcome measures (12)
- Function Acquisition Speed Test (FAST) [Time frame: Measured at baseline]
- Visual Analogue Scale (VAS) for Perceived Alignment with BPD [Time frame: Measured at baseline]
- Love Addiction Inventory (LAI) [Time frame: Measured at baseline]
- Beta-Endorphin Levels [Time frame: Measured at baseline]
- Dysfunctional Self-Perception and Related Indicators (SES) [Time frame: Measured at baseline]
- Dysfunctional Self-Perception and Related Indicators (RSES) [Time frame: Measured at baseline]
- Dysfunctional Self-Perception and Related Indicators (ESS) [Time frame: Measured at baseline]
- Dysfunctional Self-Perception and Related Indicators (VAS) [Time frame: Measured at baseline]
- Painful Experiences Related to the Relational Object (MSR) [Time frame: Measured at baseline]
- Painful Experiences Related to the Relational Object (ESUL) [Time frame: Measured at baseline]
- Painful Experiences Related to the Relational Object (RSQ) [Time frame: Measured at baseline]
- Compulsive Sexual Behavior Disorder [Time frame: Measured at baseline]
Eligibility criteria
Inclusion criteria
- General : aged 18-45
- Specific :
- Borderline personality disorder (BPD)assessed by SCID, without bipolar disorder
- Bipolar disorder (assessed by SCID), without BPD (evaluated by SCID)
- Healthy controls with no psychiatric disorders (screened by SCID).
Exclusion criteria
- Psychotic disorders (evaluated by SCID)
- lack of informed consent
- Not affiliated with social security
- Under judicial or administrative confinement or involuntary hospitalization
- Protected by law (e.g., under guardianship)
- Pregnancy or breastfeeding
- Inability to understand, speak, or write in French
- Inability to understand the study's purpose or methodology
- Excluded from another study during the exclusion period
- Participants who have received over €6000 in annual indemnities
- For Bipolar Participants (without BPD) : Current moderate or severe depressive episode (BDI score > 18) or Current hypomanic/manic episode (YMRS < 12)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Non-randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Other
Study locations
France · 1 center
- CHU Montpellier — Montpellier
Identifiers
NCT: NCT07337889 · RECHMPL24_0194