The Application of Extracellular Vesicle Detection in Gastric Juice Based on Metamaterial Sensing in the Diagnosis of Gastric Cancer and Related Diseases
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: In vitro surface plasmon resonance detection.
- Who it may be relevant to
- Registry conditions: Gastric Cancer (GC), Gastric Cancer (Diagnosis). Basic parameters: 40 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
After obtaining informed consent from the patients, all the medical history and treatment records of the patients who underwent gastroscopy since the onset of the disease, as well as gastric fluid samples, including laboratory and imaging data, were collected and recorded. The medical history and treatment records and gastric fluid samples were analyzed.
Interventions
- Diagnostic test In vitro surface plasmon resonance detection
Gastric juice from patients was removed for isolation of extracellular vesicles and surface plasmon resonance detection in vitro
Primary outcome measures
- Surface plasmon resonance(SPR) detection of extracellular vesicles in gastric juice of patients with gastric cancer has large shift and spectral changes [Time frame: baseline]
Eligibility criteria
Inclusion criteria
- Patients underwent gastroscopy and treatment at the Endoscopy Center of Beijing Friendship Hospital, Capital Medical University, and received pathological biopsy.
- Previous gastroscopy suggested the possibility of lesions.
- No previous history of gastrointestinal cancer.
Exclusion criteria
- Patients could not cooperate with the examination or had contraindications to endoscopy.
- Previous history of gastrointestinal tumors, gastrointestinal surgery, physical and chemical injuries of the gastrointestinal tract.
- Severe bile reflux.
- Take simethicone and other defoaming agents before examination.
- Patients with serious diseases of heart, lung, kidney, brain, blood and other important organs.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07332104 · BFHZS20240020 · No. BFHZS20240020