Prevalence of Cerebral Large Vessel Occlusion Among Acute Ischemic Stroke Patients in Assiut University Hospitals
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Ischemic Stroke. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals 1. Study Objectives Primary Objective: \- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals Secondary Objectives: * To describe clinical and radiological characteristics of LVO patients. * To assess factors associated with LVO (age, sex, stroke severity, comorbidities). 2. Study Design * Type: single center, prospective observational cross-sectional study * Duration: 12-month recruitment period * Setting: Assiut university hospitals, stroke unit. 3. Study Population Inclusion Criteria: * Adults (≥18 years) * Diagnosed with acute ischemic stroke within 24 hours of symptom onset * Underwent vascular imaging (CTA or MRA) on admission Exclusion Criteria: * Hemorrhagic stroke * Stroke mimics * Incomplete imaging data 4. Definitions Large Vessel Occlusion (LVO) defined as occlusion in: * Intracranial ICA * M1 or proximal M2 segments of MCA * Basilar artery ± Optional: A1 6. Data Collection Clinical Data: * Demographics (age, sex) * Risk factors (HTN, DM, AF, CAD, smoking) * NIHSS on admission and discharge mRS on admission and discharge * Onset-to-door time * Imaging modality used Imaging Data: * Site of occlusion * ASPECTS (optional) * Collateral status (optional if available) Hospital Data: * Facility type (public vs private) * Door-to-CT and door-to-CTA times 8. Analysis Plan * Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging * Subgroup analysis: By age group, sex, region, NIHSS * Secondary: Logistic regression to identify predictors of LVO
Detailed description
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals
1. Study Objectives
Primary Objective:
\- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals
Secondary Objectives: * To describe clinical and radiological characteristics of LVO patients. * To assess factors associated with LVO (age, sex, stroke severity, comorbidities). 2. Study Design
* Type: single center, prospective observational cross-sectional study * Duration: 12-month recruitment period * Setting: Assiut university hospitals, stroke unit. 3. Study Population
Inclusion Criteria:
* Adults (≥18 years) * Diagnosed with acute ischemic stroke within 24 hours of symptom onset * Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria:
* Hemorrhagic stroke * Stroke mimics * Incomplete imaging data 4. Definitions
Large Vessel Occlusion (LVO) defined as occlusion in:
* Intracranial ICA * M1 or proximal M2 segments of MCA * Basilar artery ± Optional: A1 6. Data Collection
Clinical Data:
* Demographics (age, sex) * Risk factors (HTN, DM, AF, CAD, smoking) * NIHSS on admission and discharge mRS on admission and discharge * Onset-to-door time * Imaging modality used
Imaging Data:
* Site of occlusion * ASPECTS (optional) * Collateral status (optional if available)
Hospital Data:
* Facility type (public vs private) * Door-to-CT and door-to-CTA times 8. Analysis Plan * Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging * Subgroup analysis: By age group, sex, region, NIHSS * Secondary: Logistic regression to identify predictors of LVO
Primary outcome measures
- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals [Time frame: 12 months]
Secondary outcome measures (1)
- -To describe clinical and radiological characteristics of LVO patients. - To assess factors associated with LVO (age, sex, stroke severity, comorbidities). [Time frame: 12 months]
Eligibility criteria
Inclusion criteria
- Adults (≥18 years)
- Diagnosed with acute ischemic stroke within 24 hours of symptom onset
- Underwent vascular imaging (CTA or MRA) on admission
Exclusion criteria
- Hemorrhagic stroke
- Stroke mimics
- Incomplete imaging data
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07326410 · Prevalence of Cerebral LVO