Recruiting NCT07325942
Effectiveness of Low -Versus High -Volume High -Intensity Interval Training in Patients With Chronic Heart Failure
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: low-volume high intensity interval training, High volume high intensity interval training, Standard medical treatment.
- Who it may be relevant to
- Registry conditions: Chronic Heart Failure. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
this study aims to investigate the effect of low vs high volume- high intensity interval training on functional capacity and quality of life in chronic heart failure patients
Interventions
- Other low-volume high intensity interval training
Low-volume HIIT (LV-HIIT) is a particularly time-efficient subtype of interval training, which has gained increasing attention in recent years. As per the previous definition, these brief training protocols typically involve≤10 min of intense exercise within a session lasting≤30 min including warm-up, recovery phases between intervals, and cool-down - Other High volume high intensity interval training
long (2-4 min) bouts of high (not maximum) intensity exercise interspersed with recovery periods which have wide varieties in the protocols according to the intensity, duration, and number of intervals performed - Drug Standard medical treatment
standard medical treatment for chronic heart failure as per international guidlines
Primary outcome measures
- 6 minute walk test [Time frame: at enrolment and at the end of treatment at 8 weeks]
- 2D Echocardiographic parameters [Time frame: at enrollment and at the end of treatment at 8 weeks]
Secondary outcome measures (1)
- Minnesota living with heart failure questionnaire (MLHFQ) [Time frame: at enrollment and at the end of treatment at 8 weeks]
Eligibility criteria
Inclusion criteria
- Chronic stable heart failure patient with reduced ejection fraction (EF <40)
- Age Above 18 years old
- Both males and females
- The ability to provide informed consent
Exclusion criteria
- Based on the Scientific Statement from the American Heart Association: contraindications for exercise Testing and Training. (Fletcher et al., 2013)
- Acute myocardial infarction (MI), within 2 days
- Ongoing unstable angina
- Uncontrolled cardiac tachy or brady arrhythmia with hemodynamic compromise
- Active endocarditis
- Symptomatic severe aortic stenosis
- Decompensated heart failure
- Acute pulmonary embolism, pulmonary infarction, or deep vein thrombosis
- Acute myocarditis or pericarditis
- Acute aortic dissection
- Physical disability that precludes safe and adequate testing or training
- Known obstructive left main coronary artery stenosis
- Hypertrophic obstructive cardiomyopathy with severe resting gradient
- Recent stroke or transient ischemic attack
- Mental impairment with limited ability to cooperate
- Resting hypertension with systolic or diastolic blood pressures >200/110 mmHg
- Uncorrected medical conditions, such as significant anemia, important electrolyte imbalance, and hyperthyroidism
- Acute decompensated heart failure NYHA class IV
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Cairo University — Cairo
Identifiers
NCT: NCT07325942 · P.T.REC/012/005825