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Not yet recruiting NCT07324993

Effects of a 4-week Low-intensity Training With Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain

No phase Interventional Rotator Cuff Related Shoulder Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Resistance exercise with BFR, Resistance exercise without BFR.
Who it may be relevant to
Registry conditions: Rotator Cuff Related Shoulder Pain. Basic parameters: 18 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Analysis of the Effects of a 4-week Low-intensity Training With and Without Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain

Overview

This study aims to analyze the effects of 4 weeks of low-intensity exercise with and without blood flow restriction (BFR) on pain, fear of movement, catastrophizing about pain, strength, and disability in a population with rotator cuff-related shoulder pain. There are two modalities corresponding to the same exercises under different blood flow restriction conditions: 1) 3 low-intensity exercises (30% 1RM) with BFR (50% AOP); 2) 3 low-intensity exercises (30% 1RM) without BFR. Participants will be randomly assigned to one of two groups and will undergo a 4-week intervention. The variables of interest will be assessed in each group for subsequent analysis and comparison.

Interventions

  • Device Resistance exercise with BFR
    Three exercises: external rotation at 0°, internal rotation at 0° and elevation in the scapular plane. 4 sets (30, 15, 15, reps to fatigue) with a intensity of 30% RM and a 50% of arterial occlusion pressure. 30" rest between sets, 2' rest between exercises.
  • Procedure Resistance exercise without BFR
    Three exercises: external rotation at 0°, internal rotation at 0° and elevation in the scapular plane. 4 sets (30, 15, 15, reps to fatigue) with a intensity of 30% RM and a without flow restriction application (cuff applied without pressure). 30" rest between sets, 2' rest between exercises.

Primary outcome measures

  • Pain intensity during movement (Visual Analogue Scale, 0-10) [Time frame: Baseline, 2 weeks, and 4 weeks.]
Secondary outcome measures (9)
  • Pain intensity at rest (Visual Analogue Scale, 0-10) [Time frame: Baseline, 2 weeks, and 4 weeks.]
  • Pressure pain threshold [Time frame: Before the session, immediately after, and 1 hour post-intervention]
  • Kinesiophobia [Time frame: Baseline, 2 weeks, and 4 weeks.]
  • Occurrence of adverse effects [Time frame: Immediately after the intervention, 1 hour, 6 hours, 24 hours.]
  • Pain Catastrophizing [Time frame: Baseline, 2 weeks, and 4 weeks.]
  • Pain and Disability [Time frame: Baseline, 2 weeks, and 4 weeks.]
  • Shoulder Disability [Time frame: Baseline, 2 weeks, and 4 weeks.]
  • Muscle Strength [Time frame: Baseline, 2 weeks, and 4 weeks.]
  • Satisfaction with methodology [Time frame: 4 weeks.]

Eligibility criteria

Inclusion criteria

  • Age between 18 and 65.
  • Shoulder symptoms lasting at least 3 months.
  • Pain in the proximal anterolateral aspect of the shoulder, aggravated by abduction.
  • At least two of the following tests positive: Jobe test, resisted external rotation test, Hawkins-Kennedy test, Neer test, painful arc between 60 and 120 degrees of shoulder abduction.

Exclusion criteria

  • Pain of an intensity that prevents performance of the proposed exercises.
  • Active arm elevation less than 90 degrees.
  • Clinical signs of a complete tear (positive delayed external and internal rotation sign and positive drop arm test).
  • Suspected frozen shoulder (50% reduction or more than 30° loss of passive shoulder external rotation).
  • Primary diagnosis of shoulder instability or acromioclavicular pathology.
  • Shoulder pain due to primary involvement in the cervical or thoracic region
  • Corticosteroid injection within the last 6 weeks.
  • Presence of diseases such as inflammatory arthritis, neurological diseases, fibromyalgia, malignant tumors, or polymyalgia rheumatica.
  • Presence of comorbidities that increase cardiovascular risk, such as hypertension, diabetes, or heart failure.
  • Presence of more than one thromboembolism risk factor (obesity, history of thrombosis, prolonged immobilization, recent surgery, use of contraceptives, etc.).
  • Presence of active skin lesions in the area where the sleeve will be placed, recent scars or burns, or chronic dermatological diseases that compromise skin integrity,
  • Participation in upper limb exercise programs in the last month.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07324993 · 2025-FIS-3960959

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗