A Retrospective Analysis of Robot-Assisted Versus Endoscopic Breast-Conserving Surgery for Breast Cancer
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Robotic breast-conserving surgery, Endoscopic breast-conserving surgery.
- Who it may be relevant to
- Registry conditions: Breast Cancer, Breast Surgery. Basic parameters: 18 years — 80 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Robotic surgical systems provide notable advantages including enhanced dexterity, a magnified three-dimensional high-definition view, and high-resolution imaging, thereby improving operative stability and precision. These features make robotic systems particularly suitable for procedures performed within confined operative spaces. As the breast is a solid organ without a natural cavity, robotic systems demonstrate strong adaptability for breast surgery. Robot-assisted breast-conserving surgery (RABCS) is one of the currently utilized robotic techniques in clinical breast cancer surgery. However, as robotic breast surgery remains in its early stage of development, evidence regarding the clinical outcomes of RABCS remains limited in the literature. Therefore, this study compares the surgical outcomes of endoscopic breast-conserving surgery and robot-assisted breast-conserving surgery in breast cancer patients, aiming to assess and elucidate the clinical value of RABCS.
Interventions
- Procedure Robotic breast-conserving surgery
To perform breast-conserving surgery using a robotic system, thereby validating the safety and feasibility of robotic breast-conserving surgery. - Procedure Endoscopic breast-conserving surgery
To perform breast-conserving surgery using a endoscopic system.
Primary outcome measures
- Postoperative complication rate [Time frame: 1 month postoperatively]
Secondary outcome measures (3)
- Operation time [Time frame: Intraoperative]
- Aesthetic outcomes [Time frame: 3 month postoperatively]
- Blood loss [Time frame: Perioperative]
Eligibility criteria
Inclusion criteria
- Female patients aged 18 to 80 years
- Pathologically confirmed breast cancer prior to surgery
- Sufficient glandular volume with a tumor-to-breast volume ratio ≤20%
- A unifocal lesion confined to the glandular tissue
- Clear desire for breast conservation and willingness to undergo R-BCS or E-BCS
- No evidence of distant metastasis, no involvement of the skin or chest wall
- Eligibility for standard postoperative radiotherapy
Exclusion criteria
- The presence of diffuse suspicious lesions or microcalcifications for which wide local resection was unlikely to achieve adequate negative margins or satisfactory aesthetic outcomes
- Bilateral breast cancer or inflammatory breast cancer
- After neoadjuvant therapy, requirement for additional concurrent surgical procedures
- Inability to tolerate general anesthesia or undergo surgery
- Contraindications to radiotherapy or a history of prior chest wall irradiation, pregnancy- or lactation-associated breast cancer
- Refuse to undergo R-BCS or E-BCS
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Non-randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
China · 1 center
- the Sixth Affiliated Hospital of Sun Yat-sen University — Guangzhou
Publications
- Huang Z, Fu X, Li Z, Teng Y, Pan F, Li H. Robotic versus endoscopic breast-conserving surgery: a comparative analysis of clinical outcomes and aesthetic outcomes in breast cancer. J Robot Surg. 2026 May 13;20(1):492. doi: 10.1007/s11701-026-03466-7. PMID 42126517
Identifiers
NCT: NCT07321145 · 2025ZSLYEC-374