Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Accelerated exercise, Routine exercise.
- Who it may be relevant to
- Registry conditions: Knee Osteoarthristis, Arthroplasties, Knee Replacement. Basic parameters: 50 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effectiveness of Accelerated Rehabilitation on Knee Joint Function and Quality of Life in Individuals With Total Knee Arthroplasty: A Double Blind Randomized Controlled Trial
Overview
The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to conventional rehabilitation in Dali, Yunan, China. The study will include patients aged 50-80 years who are scheduled for primary unilateral TKA. Participants will be randomly assigned to either an accelerated rehabilitation group or conventional rehabilitation group. The primary outcomes will include knee joint function, assessed using the KOOS and quality of life measures using the SF-36 surveys. The study will follow participants for 6 months post-surgery to assess longer-term outcomes. This study will not include individuals undergoing revision TKA or those with severe comorbid conditions. The results will provide critical insights into the role of accelerated rehabilitation in improving post-operative recovery, functional outcomes, and overall quality of life for TKA patients.
Interventions
- Behavioral Accelerated exercise
Based on optimal and accelerated concepts - Behavioral Routine exercise
Conventional program
Primary outcome measures
- Knee injury and Osteoarthritis Outcome Score (KOOS) [Time frame: From enrollment to the end of 6-month follow-up]
Eligibility criteria
Inclusion criteria
- Patients diagnosed with end-stage knee OA necessitating primary unilateral TKA.
Exclusion criteria
- History of joint infections, cancer, or inflammatory arthritis.
- End-stage OA from rheumatoid or septic arthritis.
- Individuals with neurological disorders such as Alzheimer's disease, - Parkinson's disease, stroke.
- Individuals who are unable to follow a structured rehabilitation protocol.
- Previous history of knee surgeries (other than arthroscopy).
- Severe comorbidities that would hinder participation (e.g., advanced cardiovascular diseases).
- Individuals who have severe osteoporosis.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- Hospital — Dali
Identifiers
NCT: NCT07319546 · MU-CIRB 2025/443.2908