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Recruiting NCT07317206

Ayahuasca, Esketamine and PTSD

Phase II Interventional Posttraumatic Stress Disorder (PTSD)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ayahuasca, Esketamine.
Who it may be relevant to
Registry conditions: Posttraumatic Stress Disorder (PTSD). Basic parameters: 18 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Brazil
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effects of Single Dose of Ayahuasca or Esketamine on Posttraumatic Stress Disorder: a Randomized, Double-blinded Study

Overview

Double-blind, randomized trial comparing a single dose of oral ayahuasca or esketamine in patients with posttraumatic stress disorder.

Interventions

  • Drug Ayahuasca
    oral ayahuasca
  • Drug Esketamine
    oral esketamine

Primary outcome measures

  • Posttraumatic Stress Disorder Checklist for DSM-5 [Time frame: From enrollment to the end of treatment at 3 weeks]

Eligibility criteria

Inclusion criteria

  • posttraumatic stress disorder

Exclusion criteria

  • psychiatric and other medical comorbidities

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Brazil · 1 center
  • Hospital das Clínicas da FMRP-USP — Ribeirão Preto

Identifiers

NCT: NCT07317206 · 55068322.2.0000.5440

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗