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Recruiting NCT07314840

Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis

— Observational Lateral Epicondylitis Lateral Elbow Tendinopathy (Tennis Elbow)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Madrid Sonographic Enthesitis Index.
Who it may be relevant to
Registry conditions: Lateral Epicondylitis, Lateral Elbow Tendinopathy (Tennis Elbow). Basic parameters: 18 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis: A Cross-Sectional Study

Overview

Lateral epicondylitis (LE) is the tendinopathy of the common extensor tendon. Although exact etiology remains unclear, it is believed to be caused by overuse. Even though, genetics factor related to tendinopathies were defined accompanying tendinopathies in patients with LE is yet to be studied. Madrid sonographic enthesitis index (MASEI) is an ultrasound based scoring system, developed for the evaluation of the enthesitis. Initially developed for ankylosing spondylitis, its usage has also become widespread in other musculoskeletal diseases. The aim of this study is to calculate the MASEI score in patients diagnosed with LE, and compare it to healthy volunteers.

Interventions

  • Diagnostic test Madrid Sonographic Enthesitis Index
    Patients will be evaluated with ultrasound at 6 different locations on each side, for total of 12 locations. These will be insertion points of triceps brachii tendon, quadriceps tendon, proximal and distal patellar tendons, achilles tendon and the plantar fascia. Evaluation parameters are the structure and thickness of the tendon, the presence of calcifications or enthesophytes, erosions in the bone, regional bursitis, and the presence of power-Doppler signal in the entheses.

Primary outcome measures

  • Madrid Sonographic Enthesitis Index [Time frame: At enrollment]

Eligibility criteria

Inclusion criteria

  • Tenderness with palpation at the lateral epicondyle
  • Pain aggravated with resisted wrist extension

Exclusion criteria

  • History of rheumatologic diseases
  • History of elbow, knee or ankle surgery
  • History of corticosteroid injections on elbow, knee or ankle
  • History of peripheral neuropathy
  • Acute trauma

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

Turkey (Türkiye) · 1 center
  • Marmara University — Istanbul

Publications

  • Ozsoy-Unubol T, Yagci I. Is ultrasonographic enthesitis evaluation helpful for diagnosis of non-radiographic axial spondyloarthritis? Rheumatol Int. 2018 Nov;38(11):2053-2061. doi: 10.1007/s00296-018-4164-4. Epub 2018 Oct 9. PMID 30302556
  • de Miguel E, Cobo T, Munoz-Fernandez S, Naredo E, Uson J, Acebes JC, Andreu JL, Martin-Mola E. Validity of enthesis ultrasound assessment in spondyloarthropathy. Ann Rheum Dis. 2009 Feb;68(2):169-74. doi: 10.1136/ard.2007.084251. Epub 2008 Apr 7. PMID 18390909
  • Okur SC, Dogan YP, Mert M, Aksu O, Burnaz O, Caglar NS. Ultrasonographic Evaluation of Lower Extremity Entheseal Sites in Diabetic Patients Using Glasgow Ultrasound Enthesitis Scoring System Score. J Med Ultrasound. 2017 Jul-Sep;25(3):150-156. doi: 10.1016/j.jmu.2017.03.011. Epub 2017 May 6. PMID 30065480
  • Johns N, Shridhar V. Lateral epicondylitis: Current concepts. Aust J Gen Pract. 2020 Nov;49(11):707-709. doi: 10.31128/AJGP-07-20-5519. PMID 33123709
  • Karanasios S, Korakakis V, Moutzouri M, Drakonaki E, Koci K, Pantazopoulou V, Tsepis E, Gioftsos G. Diagnostic accuracy of examination tests for lateral elbow tendinopathy (LET) - A systematic review. J Hand Ther. 2022 Oct-Dec;35(4):541-551. doi: 10.1016/j.jht.2021.02.002. Epub 2021 Feb 27. PMID 33814224

Identifiers

NCT: NCT07314840 · 09.2025.25-0844

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗