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Enrolling by invitation NCT07307833

Impact of Immunotherapy on Vestibular Function, The Mayo Clinic Arizona Experience

Observational Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Non-Interventional Study.
Who it may be relevant to
Registry conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

This study evaluates the impact of immunotherapy on balance in patients receiving immunotherapy as part of their standard of care.

Interventions

  • Other Non-Interventional Study
    Non-interventional study

Primary outcome measures

  • Change in clinically significant vestibulopathy - vestibular function [Time frame: Baseline, 3 months, 6 months, 12 months]
  • Change in clinically significant vestibulopathy - hearing level [Time frame: Baseline,12 months]
  • Oscillopsia Severity Questionnaire (OSQ) [Time frame: Baseline, 3 months, 6 months, 12 months]

Eligibility criteria

Inclusion criteria

  • At least 18 years of age at screening
  • Patients who will be initiating single agent immunotherapy with pembrolizumab, cemiplimab, nivolumab, atezolizumab, or dual therapy with (Ipilimumab/Nivolumab or Nivolumab/Relatlimab)

Exclusion criteria

  • Concurrent chemotherapy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Mayo Clinic in Arizona — Scottsdale

Identifiers

NCT: NCT07307833 · MC250709 · NCI-2025-08558 · 22-009510 · MC250709

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗