Not yet recruiting NCT07306975
Comparative Analysis of SUV Measurements Using Different Correction Methods in Oncological PET/CT Imaging.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: PET/CT with 18-FDG.
- Who it may be relevant to
- Registry conditions: Cancer Patients Referred to do PET/CT Study. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
-To measure SUVs by using different correction methods in oncological PET/CT imaging.
Detailed description
-To compare between SUV measurements in the tumor and liver using different standardizing parameters such as: body weight, lean body mass and body surface area.
Interventions
- Device PET/CT with 18-FDG
* Patients will fast for at least 4 hrs before imaging with blood glucose level (\<200 mg/dl) before intravenous administration of F18-FDG. * Imaging will be performed approximately 45 to 60 min after 18F-FDG injection, an imaging field of view from the base of skull to mid-thighs with the arms above the head whenever possible is used or otherwise the arms are positioned beside the body.
Primary outcome measures
- -To measure SUVs by using different correction methods in oncological PET/CT imaging. [Time frame: 1/12/2025 to 1/10/2027]
Secondary outcome measures (1)
- To determine if SUVbsa is more accurate than SUVbw in obese patients. [Time frame: 1/12/2025 to 1/10/2027]
Eligibility criteria
Inclusion criteria
- Cancer patients (> 18 years old) referred to nuclear medicine unit to do F18-FDG PET/CT study.
Exclusion criteria
- Patients < 18 years old.
- Patients with increased FDG uptake on tissue associated with non-malignant causes such as diffuse bone marrow FDG uptake or inflammatory.
- Patients with extensive metastasis.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Kim CK, Gupta NC, Chandramouli B, Alavi A. Standardized uptake values of FDG: body surface area correction is preferable to body weight correction. J Nucl Med. 1994 Jan;35(1):164-7. PMID 8271040
- Nakaichi T, Funamoto K, Yamashita S, Yamamoto H, Yokoyama K. Clinical Usefulness of Standardized Uptake Value Normalized to Lean Body Mass Measured Using a Body Composition Analyzer. Cureus. 2025 May 30;17(5):e85089. doi: 10.7759/cureus.85089. eCollection 2025 May. PMID 40589668
- Azmi NHM, Suppiah S, Liong CW, Noor NM, Said SM, Hanafi MH, et al. Reliability of standarized uptake value normalized to lean body mass using the liver as a reference organ, in contrast-enhanced 18F-FDG PET/CT imaging. Radiography. 2018;24(2):112-117. doi:10.1016/j.radi.2017.09.006.
- Ahmed A, Ali M, Salah H, Eisa RE, Mohieldin H, Omer H, et al. Evaluation of uptake values of FDG: Body surface area Vs. body weight correction. Radiat Phys Chem. 2022;201:110482. doi:10.1016/j.radphyschem.2022.110482 .
Identifiers
NCT: NCT07306975 · SUV measurements in PET/CT