Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sevoflurane (Volatile Anesthetic), Desflurane (volatile anesthetic).
- Who it may be relevant to
- Registry conditions: Respiratory Mechanics, Intraoperative. Basic parameters: 18 years — 87 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Greece
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery on Airway Plateau Pressure: a Randomized, Prospective, Blinded Pilot Study
Overview
Inhalational anesthetics, when used in abdominal surgery, offer advantages of lung protection and reduced alveolar inflammation. There is little literature, however, in the comparative use of sevoflurane versus desflurane anesthesia in patients undergoing abdominal robotic-assisted surgery and their effects on lung mechanics.
Interventions
- Drug Sevoflurane (Volatile Anesthetic)
Sevoflurane for robotic assisted laparoscopic surgery - Drug Desflurane (volatile anesthetic)
Desflurane for robotic assisted laparoscopic surgery
Primary outcome measures
- airway plateau pressure [Time frame: Perioperatively]
Eligibility criteria
Inclusion criteria
- Age 18 to 87 years
- Undergoing elective robotic-assisted abdominal surgery
- ASA physical status I-III
Exclusion criteria
- ASA IV or V
- Emergency surgery
- Renal insufficiency
- Clinically significant respiratory disease
- Cardiomyopathy
- Uncontrolled hypertension
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Prevention
Study locations
Greece · 1 center
- Aretaieion University Hospital — Athens
Publications
- Herling SF, Dreijer B, Wrist Lam G, Thomsen T, Moller AM. Total intravenous anaesthesia versus inhalational anaesthesia for adults undergoing transabdominal robotic assisted laparoscopic surgery. Cochrane Database Syst Rev. 2017 Apr 4;4(4):CD011387. doi: 10.1002/14651858.CD011387.pub2. PMID 28374886
Identifiers
NCT: NCT07304479 · 705/25-07-2025