Prevalence of Sarcopenia in Patients Admitted to ICU and Its Progression During Hospitalization.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Sarcopenia, Critical Illness, Intensive Care (ICU) Myopathy, Body Composition Measurement. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Spain
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This is a prospective, observational study at the ICU of Hospital Mútua de Terrassa, running from May to December 2025. The primary goal is to determine the prevalence of sarcopenia in adult patients requiring more than 48 hours of mechanical ventilation. Sarcopenia is assessed using the SARC-F score, impedanciometry, and quadriceps ultrasound. Secondary aims include tracking the development of ICU-Acquired Weakness (ICU-AW) using the MRC score. All data is collected anonymously after obtaining informed consent.
Primary outcome measures
- Prevalence of sarcopenia at the time of ICU admission. [Time frame: Baseline at admission to ICU]
Secondary outcome measures (2)
- Detecting patients who develop ICU-Acquired Weakness (ICU-AW) and/or prolonged mechanical ventilation weaning [Time frame: From ICU admission to 30 days follow-up]
- Detecting the appearance of other complications [Time frame: From admission to 30 days follow up]
Eligibility criteria
Inclusion criteria
- Older than 18 years old.
- Expected duration of mechanical ventilation (MV) exceeding 48 hours.
Exclusion criteria
- Refusal to participate.
- Mechanical ventilation not exceeding 48 hours.
- Do-not-resuscitate (DNR) orders or limitations of therapeutic effort upon admission.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Spain · 1 center
- Hospital Universitari Mútua Terrassa — Terrassa
Publications
- Sostakaite G, Jauniskyte M, Budrys D, Budrevicius K, Salciute-Simene E, Svetikiene M, Jovaisa T, Zvirblis T, Klimasauskas A, Sipylaite J. Comparison of Two Techniques to Assess Muscle Mass Loss During ICU Stay: Muscle Ultrasound vs Bioelectrical Impedance Analysis. Nutrition. 2025 Feb;130:112607. doi: 10.1016/j.nut.2024.112607. Epub 2024 Oct 24. PMID 39549651
- Nakanishi N, Tsutsumi R, Okayama Y, Takashima T, Ueno Y, Itagaki T, Tsutsumi Y, Sakaue H, Oto J. Monitoring of muscle mass in critically ill patients: comparison of ultrasound and two bioelectrical impedance analysis devices. J Intensive Care. 2019 Dec 16;7:61. doi: 10.1186/s40560-019-0416-y. eCollection 2019. PMID 31890223
Identifiers
NCT: NCT07303335 · P/25-054/Fundació assistencial · Mutua Terrassa