Multimodal Physiotherapy and Pain Coping in Primary Care
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Multimodal Physiotherapy Program Based on Pain Neuroscience Education and Therapeutic Exercise.
- Who it may be relevant to
- Registry conditions: Chronic Musculoskeletal Pain. Basic parameters: 18 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Multimodal Physiotherapy Intervention for Active Coping With Persistent Musculoskeletal Pain in Primary Care
Overview
This quasi-experimental, multicenter study aims to evaluate the effectiveness of a multimodal physiotherapy intervention-based on pain neuroscience education and therapeutic exercise-on health-related quality of life in patients with persistent musculoskeletal pain treated in Primary Care. The study will be conducted in four Primary Care physiotherapy units in the Valencian Community (Spain). A total of at least 68 participants aged 18 to 70 years with nonspecific persistent musculoskeletal pain lasting at least six months will be recruited. The intervention will consist of a structured multimodal physiotherapy program including educational sessions on pain neuroscience and guided therapeutic exercise. The main outcome will be health-related quality of life, assessed using the SF-36 Health Survey. Secondary outcomes will include pain catastrophizing (Pain Catastrophizing Scale), kinesiophobia (Tampa Scale for Kinesiophobia), and central sensitization (Central Sensitization Inventory), among others. Data will be collected using the REDCap electronic platform at three time points: baseline (pre-intervention), immediately after the intervention, and six months post-intervention. Statistical analysis will include descriptive statistics, bivariate analyses, and paired comparisons to assess changes over time. The study seeks to generate evidence on the feasibility and potential effectiveness of implementing a multimodal physiotherapy intervention for active coping with chronic musculoskeletal pain in the context of Primary Care.
Interventions
- Behavioral Multimodal Physiotherapy Program Based on Pain Neuroscience Education and Therapeutic Exercise
The intervention consists of a multimodal physiotherapy program designed to promote active coping and improve health-related quality of life in patients with persistent musculoskeletal pain. It includes educational sessions on pain neuroscience aimed at reconceptualizing pain and reducing maladaptive beliefs, combined with supervised therapeutic exercise focused on mobility, strength, and functional recovery. The program will be delivered in small group sessions by trained physiotherapists in Pr
Primary outcome measures
- Health-Related Quality of Life Measured With the 36-Item Short Form Health Survey (SF-36) [Time frame: Baseline (before the intervention), immediately after the intervention, and 6 months after the intervention.]
Secondary outcome measures (6)
- Pain Catastrophizing Measured With the Pain Catastrophizing Scale (PCS) [Time frame: Baseline (before the intervention), immediately after the intervention, and 6 months after the intervention.]
- Kinesiophobia Assessed Using the Tampa Scale for Kinesiophobia (TSK-11 or TSK-17) [Time frame: Baseline (before the intervention), immediately after the intervention, and 6 months after the intervention.]
- Central Sensitization Assessed With the Central Sensitization Inventory (CSI) [Time frame: Baseline (before the intervention), immediately after the intervention, and 6 months after the intervention.]
- Pain Intensity Measured Using the Numerical Rating Scale (NRS 0-10) [Time frame: Baseline (before the intervention), immediately after the intervention, and 6 months after the intervention.]
- Treatment Adherence Assessed With a Session Attendance Log [Time frame: During the intervention period]
- Patient Satisfaction Measured With a Likert-Type Satisfaction Questionnaire [Time frame: Immediately after the intervention.]
Eligibility criteria
Inclusion criteria
\- Persistent nonspecific musculoskeletal pain lasting at least 6 months
Exclusion criteria
- Oncologic pain.
- Spinal fracture or surgical intervention within the 12 months prior to the intervention.
- Cognitive impairment that prevents comprehension of the intervention content (in case of doubt, the Mini-Mental State Examination will be administered, requiring a minimum score of 25).
- Physical performance deficit that prevents execution of the intervention (minimum requirement: completion of the Timed Up and Go test within the normal time of 10 seconds).
- Pregnancy.
- Cauda equina syndrome.
- Presence of urinary and/or fecal incontinence.
- Severe psychiatric disorders.
- Autoimmune diseases.
- Associated medical conditions that preclude participation in a physical exercise program (e.g., myopathies, neurological diseases with significant functional impairment).
- Patients undergoing alternative therapies.
- Patients with an implanted neurostimulator.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07299929 · DC-GVA-2025