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Not yet recruiting NCT07297615

3D Liver Volumetry

No phase Interventional Liver Surgery Liver Cancer Surgical Planning Liver

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: 3d reconstruction.
Who it may be relevant to
Registry conditions: Liver Surgery, Liver Cancer, Surgical Planning, Liver. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Austria
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Accuracy of Individualized 3D Reconstruction in Predicting Liver Resection Volume: A Prospective Study

Overview

The study aims to improve preoperative evaluation of liver resection volume in patients undergoing major hepatectomies. Accurate prediction of the planned resection and the future liver remnant (FLR) is critical to minimize the risk of postoperative liver failure, which is associated with increased morbidity and mortality. Conventional imaging-based volumetry may have limited accuracy. This study investigates the use of individualized 3D liver models combined to enhance visualization and volumetric analysis of liver anatomy and resection boundaries. Patients are recruited in the liver outpatient clinic and, upon consent, preoperative 3D models are created using Medics 3D. During surgery, the planned resection is guided by the individualized 3D models. Postoperatively, the resected specimen undergoes CT-based volumetry to compare the predicted resection volume from the 3D model with the actual volume. Routine postoperative follow-up is conducted. The study aims to optimize surgical planning, enhance the accuracy of future liver remnant prediction.

Interventions

  • Diagnostic test 3d reconstruction
    Preoperatively, every patient in this study will undergo an individualized 3D reconstruction of their liver to perform accurate volumetry.

Primary outcome measures

  • Assessment of the preoperative volumetry of the liver portion planned for resection using a 3D model and comparison with the postoperative resection specimen volume. [Time frame: Approximately 2-3 weeks are required between preoperative volumetry and postoperative volumetry comparison.]

Eligibility criteria

Inclusion criteria

  • Adult patients (≥18 years) undergoing open or minimally invasive major liver resection at the Clinical Division of General, Visceral and Transplant Surgery who provide written informed consent prior to participation will be included.

Exclusion criteria

  • Patients unable to provide informed consent will be excluded.
  • Minor resections.
  • Contraindications to MRI.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Other

Study locations

Austria · 1 center
  • Medical University of Graz - Department of Surgery, Division of General, Visceral and Tran — Graz

Identifiers

NCT: NCT07297615 · 1465/2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗