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Recruiting NCT07296926

Distolingual Infiltration Verses Conventional Nerve Block in Mandibular Third Molar Extraction

No phase Interventional Pain (Visceral, Somatic, or Neuropathic)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Conventional Inferior Alveolar and Buccal Nerve Block, Distolingual Infiltration plus Conventional Nerve Block.
Who it may be relevant to
Registry conditions: Pain (Visceral, Somatic, or Neuropathic). Basic parameters: 18 years — 45 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparison of Efficacy of Distolingual Infiltration in Conjugation With Conventional Inferior Alveolar Nerve Block to Conventional Inferior Alveolar Nerve Block Alone for Extraction of Mandibular Third Molar

Overview

This randomized controlled trial will compare the effectiveness of adding distolingual infiltration to conventional inferior alveolar and buccal nerve blocks for mandibular third molar extraction. A total of 120 patients will be allocated into two groups. Pain during flap elevation and bone guttering will be assessed using the Visual Analogue Scale.

Detailed description

Mandibular third molar extraction is a common oral and maxillofacial surgery procedure that requires profound local anesthesia. Despite conventional inferior alveolar, lingual and buccal nerve blocks, the distolingual gingiva may remain non-anesthetized due to accessory innervation via the mylohyoid and other nerves. Distolingual infiltration may improve anesthesia in this area.

This randomized controlled trial will enroll 120 patients requiring mandibular third molar extraction. Participants will be randomized into two groups: conventional inferior alveolar and buccal nerve block (Group A) and the same technique with additional distolingual infiltration (Group B). Pain during mucoperiosteal flap elevation and bone guttering will be recorded on a 0-10 Visual Analogue Scale. The primary objective is to determine whether distolingual infiltration improves pain control compared to the conventional technique.

Interventions

  • Procedure Conventional Inferior Alveolar and Buccal Nerve Block
    Standard inferior alveolar and long buccal nerve block for mandibular third molar extraction.
  • Procedure Distolingual Infiltration plus Conventional Nerve Block
    Distolingual infiltration (0.2 ml) administered in addition to conventional inferior alveolar during mandibular third molar extraction.

Primary outcome measures

  • Pain during mucoperiosteal flap elevation [Time frame: During mucoperiosteal flap elevation on the day of surgery]
  • Pain During Bone Guttering [Time frame: During bone guttering on the day of surgery.]

Eligibility criteria

Inclusion criteria

  • Healthy individuals
  • Male and female
  • Age 18-45 years
  • Mandibular third molar impaction - all positions
  • Mandibular third molar impaction - all classes

Exclusion criteria

  • ASA status III and above
  • Patients requiring multiple extractions in the same appointment
  • Allergy to lignocaine
  • Patients in whom adrenaline is contraindicated
  • Medically compromised individuals e.g. poorly controlled diabetes, hypertension

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Pakistan · 1 center
  • Dr Aimen Zafar — Islamabad

Identifiers

NCT: NCT07296926 · DSG-2023-335-4631-A

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗