Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Group patients based on whether they have been diagnosed with PSD..
- Who it may be relevant to
- Registry conditions: Post-stroke Depression. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Post-stroke depression (PSD) is the most common neuropsychiatric disorder after a stroke, with an incidence rate of 20% to 60%. PSD is not only associated with higher mortality rates, poorer recovery, more obvious cognitive impairments, greater economic burdens, and lower quality of life, but also brings additional medical expenses and care pressure to families. Society also needs to bear higher medical costs. Currently, the early diagnosis of PSD is difficult, which may lead to poor prognosis after stroke. This study aims to utilize machine learning technology to integrate multi-dimensional indicators of patients with ischemic stroke, establish a risk prediction model for PSD, and assist in early, accurate, and individualized assessment of PSD risk in clinical practice.
Interventions
- Diagnostic test Group patients based on whether they have been diagnosed with PSD.
Group patients based on whether they have been diagnosed with PSD.
Primary outcome measures
- The number of post-stroke depression (PSD) that occurs 3 months after stroke [Time frame: 3 months after stroke]
Eligibility criteria
Inclusion criteria
- Patients with acute ischemic stroke;
- Admission within 7 days of symptom onset;
- The patient and/or the family members sign a written informed consent form.
Exclusion criteria
- Confusion of consciousness,severe cognitive impairment, etc
- Individuals with a history of depression, schizophrenia, bipolar disorder, etc;
- Individuals unable to participate in neuropsychological examinations due to hearing im pairments, lack of coordination, or neurological deficits, including se vere aphasia.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- The First Affiliated Hospital of Chongqing Medical University — Chongqing
Identifiers
NCT: NCT07294274 · 20251114