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Not yet recruiting NCT07292675

The Effect of Low Intensity With BFR on Stroke Patients

No phase Interventional Ischemic Stroke

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: low-intensity resistance training with blood flow restriction, High intensity resistance training.
Who it may be relevant to
Registry conditions: Ischemic Stroke. Basic parameters: 30 years — 50 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Effect of Low Intensity Training With Blood Flow Restriction Versus Traditional Resistance Exercise on Lower Extermity Isokinetic Torque and Balance in Ischemic Stroke Patients

Overview

To compare the effects of low-intensity resistance training with blood flow restriction (BFR) versus traditional resistance training on lower limb isokinetic torque and dynamic balance in ischemic stroke survivors.

Detailed description

Ischemic stroke commonly results in reduced lower extremity muscle torque and impaired balance, affecting mobility and fall risk.

Traditional resistance training improves muscle function but may not be suitable for all patients due to the need for high mechanical loads.

Low-intensity resistance training with blood flow restriction (BFR) has emerged as an alternative that enhances muscular adaptation at lower loads. However, limited data exists on its effect on isokinetic torque and functional balance in stroke patients. This study aims to fill this gap using objective isokinetic measurements and validated balance scales.

Interventions

  • Other low-intensity resistance training with blood flow restriction
    "Low-Intensity" BFR Means (for Quads) It involves resistance 20-30% 1RM combined with partial arterial + full venous restriction using a cuff placed on the proximal thigh.
  • Other High intensity resistance training
    High-intensity quadriceps training in stroke patients focuses on using 60-80% of 1RM to improve strength, motor unit recruitment, and functional mobility. Exercises such as loaded sit-to-stand, leg press, and step-ups are commonly used to target the quadriceps safely. Training intensity is guided by a perceived exertion of 7-9/10 while maintaining proper supervision to prevent falls. This approach enhances knee stability, gait efficiency, and overall functional independence.

Primary outcome measures

  • Isokinetic torque [Time frame: Baseline]

Eligibility criteria

Inclusion criteria

  • • First-ever ischemic stroke (3-12 months post-stroke)
  • Aged 30-40 years
  • Can walk independently or with an aid
  • Medically stable and able to follow instructions

Exclusion criteria

  • •Hemorrhagic stroke
  • Deep vein thrombosis or peripheral vascular disease
  • Orthopedic conditions affecting lower limb
  • Severe cognitive impairment or uncontrolled hypertension

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07292675 · P.T.REC/012/005961

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗