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Recruiting NCT07291765

Blood Flow Restriction Training in Acute Geriatric Rehabilitation

No phase Interventional Sarcopenia in Elderly

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Stationary Bike + Blood-Flow-Restriction, Stationary Bike + Sham-Blood-Flow-Restriction.
Who it may be relevant to
Registry conditions: Sarcopenia in Elderly. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Germany
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Blood Flow Restriction Training in Acute Geriatric Rehabilitation: A Randomized Controlled Trial on Its Effects and Safety in Hospitalized Older Adults.

Overview

Background: Older adults have a reduced ability to build and maintain muscle mass due to age-related changes in the muscular system. The resulting sarcopenia can lead to a number of health problems and limitations, such as an increased risk of falling and reduced mobility, which can affect quality of life and increase the risk of disease. To increase muscle mass and strength, high-intensity resistance training with loads of 70 to 85% of the repetition maximum (1RM) is recommended. However, this type of training poses a major challenge in the rehabilitation sector, as there is also an increased risk of injury due to physical limitations in old age. According to current research, low-intensity occlusion training could therefore represent a safe and effective training alternative. The aim of this study is therefore to examine the feasibility and effects of blood flow restriction training (BFR) on general health in older adults in a rehabilitative setting.

Detailed description

The study is a randomized controlled trial with a pre-post design. Participants will be recruited from the of St. Marien Hospital Geriatric Rehabilitation Center in Cologne, Germany. Patients will be randomized into 2 groups. The intervention group will receive BRF training on a stationary cycling ergometer five times a week over a period of two weeks, while the control group will receive sham-BFR training.

Interventions

  • Device Stationary Bike + Blood-Flow-Restriction
    Cycling Intensity individualized + 60% LOP
  • Device Stationary Bike + Sham-Blood-Flow-Restriction
    Cycling Intensity individualized + 20mmHg

Primary outcome measures

  • Muscle Strength [Time frame: Pre-Rehabilitation to Post-Rehabilitation (after 2 weeks)]
  • Timed Up and Go Test [Time frame: Pre-Rehabilitation to Post-Rehabilitation (after 2 Weeks)]

Eligibility criteria

Inclusion criteria

  • Adults >65 years with a two week hospitalized acute rehabilitation after a fracture closed to the hip joint

Exclusion criteria

  • Sickle Cell Anemia
  • Iatrogenic changes of the vessels at the place of the tournqiuet application (e.g. Stents)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Germany · 1 center
  • St. Marien-Hospital Köln — Cologne

Identifiers

NCT: NCT07291765 · 2025_A

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗