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Not yet recruiting NCT07287579

Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in HairTransplantation

No phase Interventional Androgenic Alopecia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: hair transplantation.
Who it may be relevant to
Registry conditions: Androgenic Alopecia. Basic parameters: 20 years — 50 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparison Between Platelet Rich Plasma and Nanofat as an Adjuvant Therapy in Hair Transplantation in Male Androgenic Alopecia

Overview

* To compare the efficacy of platlet rich plasma and Nanofat injection as adjuvant therapies with FUE hair transplantation in improving graft survival rate, * To measure hair density and thickness postoperatively using dermoscopy or trichoscopy. * To evaluate patient satisfaction and photographic assessment by blinded evaluators. * To assess any adverse effects or complications related to each modality

Detailed description

* Ideal candidates for hair transplantation typically present with a clear, stable pattern of hair loss, characterized by at least 50% thinning or balding in 1 or more areas. The scalp must be healthy, with donor hair of good quality and quantity. Patients must have realistic expectations and be free of medical conditions that compromise surgical outcomes. The safe donor zone is located in the mid-occipital region between the upper and lower occipital protuberances, typically containing 65 to 85 follicular units/cm² * Intra-operative injection of PRP is beneficial in giving faster density, reducing the catagen loss of transplanted hair, early recovery of the skin, the faster appearance of new anagen hair in FUE hair transplantation. * This study compares the effects of PRP and Nano fat as adjuvants in Androgenic alopecia patients undergoing FUE hair transplantation. * Nanofat contain stem cells supposed to improve the results of FUE hair transplantation , but the question that we hope to answer at the end of our study which one we recommend as an adjuvant therapy PRP or Nano fat?

Interventions

  • Procedure hair transplantation
    we compare the effect of nanofat injection and platelet rich plasma in hair transplantation in male androgenic alopecia

Primary outcome measures

  • • To measure hair density using dermoscopy. [Time frame: • All patients will be followed up about 6-12 months postoperative.]

Eligibility criteria

Inclusion criteria

  • 1\. Male patients with stable androgenic alopecia more than 2 years. 2. Age 20-50 years 3. No recent medical hair loss treatments.

Exclusion criteria

  • 1\. Active scalp infections or scarring alopecia. 2. Systemic diseases affecting wound healing. 3. Platelet disorders or anticoagulant use. 4. Smoking or heavy alcohol intake

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Publications

  • Evin N, Guray Evin S. Camouflage of Postburn Scarring Alopecia Using Nanofat Grafting and Follicular Unit Hair Transplantation. Plast Reconstr Surg. 2024 Jul 1;154(1):207-215. doi: 10.1097/PRS.0000000000010759. Epub 2023 May 26. PMID 37253046

Identifiers

NCT: NCT07287579 · Soh-Med--25-11-1MD

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗