Effect of High-intensity Interval Training on Cardiometabolic Health and Physical Fitness in Young Adults With Obesity
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: High-intensity interval training intervention, Moderate-intensity continuous training intervention, Educational sessions.
- Who it may be relevant to
- Registry conditions: Obesity & Overweight. Basic parameters: 18 years — 35 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Mexico
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The objective of the present project is to compare the effects of two types of training on cardiovascular health components and physical fitness in young adults with obesity.
Detailed description
Obesity represents a serious public health problem, and its prevalence continues to rise worldwide. Numerous studies have documented the positive effects of moderate-intensity continuous training (MICT) on cardiovascular and metabolic health in individuals living with obesity; however, the effects of high-intensity interval training (HIIT) are still being explored.
Therefore, the objective of the present research protocol is to analyze and compare the effects of an MICT program and an HIIT program on cardiometabolic biomarkers and physical fitness in young adults with obesity.
Interventions
- Other High-intensity interval training intervention
The HIIT group will undergo training for 12 weeks, with a frequency of three sessions per week, completing a total of 36 sessions. Each session will include a 5-minute warm-up and a 5-minute cool-down at 50-60% of maximum heart rate (HRmax). The training protocol will consist of 2-minute high-intensity intervals performed at 90-95% HRmax, corresponding to a Borg rating of perceived exertion (RPE) of 17-18, alternated with 2-minute recovery periods at 70% HRmax (RPE 12-14). A total of five interv - Other Moderate-intensity continuous training intervention
The MICT group will perform moderate-intensity continuous training at 60-70% HRmax, corresponding to an RPE of 12-14, for 35-45 minutes on a stationary cycleergometer. Heart rate and physical activity levels will be continuously monitored in both groups using a chest-strap heart rate sensor (Polar H9, Polar Electro, Finland). - Other Educational sessions
In addition, four educational sessions will be conducted to provide dietary recommendations to all participants. These sessions will aim to promote balanced eating habits and to discourage the excessive consumption of ultra-processed foods or alcohol, as these factors could interfere with the intervention outcomes.
Primary outcome measures
- Maximum oxygen uptake (VO₂max) [Time frame: Baseline and after 12 weeks]
- Weight [Time frame: Baseline and after 12 weeks]
- Height [Time frame: Baseline and after 12 weeks]
- Body mass index (BMI) [Time frame: Baseline and after 12 weeks]
- Body fat percentage [Time frame: Baseline and after 12 weeks]
- Muscle mass percentage [Time frame: Baseline and after 12 weeks]
- Waist circumference [Time frame: Baseline and after 12 weeks]
- Waist-to-hip ratio [Time frame: Baseline and after 12 weeks]
- Glucose [Time frame: Baseline and after 12 weeks]
- Triglycerides [Time frame: Baseline and after 12 weeks]
Eligibility criteria
Inclusion criteria
- Young adults
- BMI ≥ 30 kg/m\^2" and < 40 kg/m\^2
- Signed informed consent form
Exclusion criteria
- Participants who smoke
- Clinical diagnosis of hypothyroidism
- Clinical diagnosis of type 1 diabetes mellitus
- Clinical diagnosis of type 2 diabetes mellitus
- Clinical diagnosis of grade 3 obesity
- Clinical diagnosis of hypertension
- Clinical diagnosis of acute myocardial infarction or angina pectoris
- Use of nitrates and calcium channel blockers within 4 days prior to the start of the study
- Use of beta-blockers or hypoglycemic agents within 7 days prior to the intervention
- Pregnant women
- Breastfeeding women
- Men consuming more than 40 g of alcohol per day or women consuming more than 20 g per day
- Postural and biomechanical disorders (knee, foot, and spine)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Mexico · 1 center
- Centro Universitario de Tlajomulco, Universidad de Guadalajara — Guadalajara
Identifiers
NCT: NCT07283406 · CUTLAJO251028