Psychological Support Interventions for Women With Endometriosis (ENDOPSY)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Individual Psychotherapy, Socio-Aesthetic Group Therapy, Mixed Psychotherapy.
- Who it may be relevant to
- Registry conditions: Endometriosis. Basic parameters: from 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Psychological Support Interventions and Their Effect on Quality of Life and Psychological Functioning in Women With Endometriosis: A Randomized Controlled Trial (ENDOPSY)
Overview
Endometriosis is associated with severe pain, impaired quality of life and significant psychological distress. Psychological support may help improve emotional regulation, mental health, and quality of life in affected women. This randomized controlled trial evaluates the impact of three psychological support interventions-individual psychotherapy, socio-aesthetic group therapy, and a mixed approach combining both-on psychological symptoms and quality of life. Forty participants will be randomized into four parallel arms. The study hypothesis is that psychological support interventions improve psychological functioning and disease-related quality of life compared with no intervention, and that the combined mixed approach may produce greater benefits than the individual or group interventions alone.
Interventions
- Behavioral Individual Psychotherapy
Ten individual psychotherapy sessions (45 minutes each) delivered every two weeks for 5 months by trained psychologists. - Behavioral Socio-Aesthetic Group Therapy
Six socio-aesthetic therapy workshops (2 hours each) every two weeks over 3 months, focusing on body image, sensory experience, and emotional expression. - Behavioral Mixed Psychotherapy
Combined individual and group psychotherapy including alternating sessions and final integrative sessions matching the number and duration of individual and group interventions.
Primary outcome measures
- Change in Endometriosis-Related Quality of Life (EHP-30 score) [Time frame: Baseline (T1) and 5 months (T2)]
Secondary outcome measures (5)
- Change in Anxiety Symptoms (HADS-A score) [Time frame: Baseline and 5 months]
- Change in Depression Symptoms (HADS-D score) [Time frame: Baseline and 5 months]
- Change in Alexithymia (TAS-20 score) [Time frame: Baseline and 5 months]
- Change in Emotion Regulation (ERQ scores) [Time frame: Baseline and 5 months]
- Qualitative Themes Emerging From Semi-Structured Interviews [Time frame: Baseline and 5 months]
Eligibility criteria
Inclusion criteria
- Adult women ≥18 years
- Clinical diagnosis of endometriosis
- Ability to understand and complete psychological evaluations
- Signed written informed consent
Exclusion criteria
- Ongoing psychotherapy
- Cognitive, sensory or language impairments preventing participation
- Participation in another interventional clinical study
- Persons under legal protection
- Non-French speakers
- Pregnancy or breastfeeding
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Supportive care
Study locations
France · 1 center
- Hôpital Lyon Sud - Hospices Civils de Lyon — Pierre-Bénite
Identifiers
NCT: NCT07280052 · 69HCL25_0655 · 2025-A02054-45