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Recruiting NCT07277686

AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population

— Observational Coronary Artery Disease (CAD) Artificial Intelligence Algorithms Face Screening

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: No Intervention.
Who it may be relevant to
Registry conditions: Coronary Artery Disease (CAD), Artificial Intelligence Algorithms, Face, Screening. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Overview

This study aims to evaluate the effectiveness of this facial image-based AI algorithm for screening CAD in high-risk community populations (specifically individuals with diabetes, hypertension, or aged over 65). The main objectives are: 1. To verify if the AI algorithm can accurately distinguish between high-risk and low-risk groups by comparing the actual prevalence of CAD in these groups. 2. To compare the CAD detection rate using this AI screening strategy against the natural detection rate in a real-world cohort.

Interventions

  • Other No Intervention
    No Intervention

Primary outcome measures

  • Difference in Prevalence of CAD Between AI-Stratified High-Risk and Low-Risk Groups [Time frame: Up to 6 months]
Secondary outcome measures (6)
  • The detection rate of CAD [Time frame: 6 months]
  • Incidence of Major Adverse Cardiovascular Events (MACE) [Time frame: 6 months]
  • Incidence of All-Cause Death [Time frame: 6 months]
  • Incidence of Myocardial Infarction [Time frame: 6 months]
  • Incidence of Ischemia-Driven Coronary Revascularization [Time frame: 6 months]
  • Incidence of Screening-Driven Coronary Revascularization [Time frame: 6 months]

Eligibility criteria

Inclusion criteria

  • Age >= 18 years.
  • Community high-risk population, defined as individuals meeting at least one of the following criteria:
  • Diagnosed with Diabetes Mellitus;
  • Diagnosed with Hypertension;
  • Advanced age (> 65 years old).

Exclusion criteria

  • Prior confirmed diagnosis of Coronary Heart Disease (CAD), including clinically diagnosed CAD, history of Coronary Artery Bypass Grafting (CABG), or history of Percutaneous Coronary Intervention (PCI).
  • History of diagnosed Heart Failure.
  • Significant facial alterations or conditions that may interfere with AI image analysis, such as plastic surgery, severe facial trauma, or heavy makeup.
  • Refusal to participate in the study.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

China · 3 centers
  • Zhoukou Chuanhui District Hospital of Traditional Chinese Medicine — Zhoukou
  • Zhoukou Specialized Disease Hospital — Zhoukou
  • Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College — Beijing

Identifiers

NCT: NCT07277686 · 2025-ZX165

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗