Analysis of The Outcomes of Therapeutic Photorefractive Keratectomy Combined With Prophylactic Accelerated Cross-Linking (PRK-Plus), for Treatment of Thin Suspicious Cornea
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: PRK PLUS.
- Who it may be relevant to
- Registry conditions: Thin Suspicious Cornea. Basic parameters: 18 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Analysis of The Outcomes of Therapeutic Photorefractive Keratectomy Combined With Prophylactic Accelerated Cross-Linking (PRK-Plus), for Treatment of Thin Suspicious Cornea: Short-Term Pilot Study
Overview
analyze the outcomes of therapeutic photorefractive keratectomy combined with prophylactic accelerated cross-linking (PRK-Plus), for treatment of thin suspicious cornea
Interventions
- Procedure PRK PLUS
therapeutic photorefractive keratectomy combined with prophylactic accelerated cross-linking
Primary outcome measures
- visual acuity improvement measured by LogMAR system [Time frame: 1 year]
Eligibility criteria
Inclusion criteria
- CCT less than 490 microns
- K mean more than 46 and/or K max more than 47.
- Astigmatism cylinder >1.5 D.
- D value of Belin/Ambrósio Module > 1.6
- inferior- superior asymmetry or bow-tie pattern with skewed radial axes on tangential maps and abnormal changes on (BAD).
- Asymmetry topography between 2 eyes, even if neither eye"s topographic pattern is in itself decidedly abnormal.
- Any significant skewed radial axis with or without inferior steepening, or one diopter or more of inferior steepening in some areas but an I-S value of ,1.4,7.
- young patients with against-the-rule astigmatic patterns.
- a PTA value 40% if calculated.
- Abnormal Topographic Patterns
- K2 reading of corneal back surface less than \[-7\].
- D Value of CSTP > 2.5 in Belin/Ambrósio curve
- We look at values within the central 5 mm circle; the map should be displayed in the BFTE float mode with an estimated area of 8 mm of diameter:
- Elevation values on the front surface values > +12 μ
- Elevation values on the back surface values >+15 μ.
- If there is any isolated island on either front or back surfaces (in the BFS float mode)
Exclusion criteria
- Eyes diagnosed with KC.
- CCT less than 450 microns
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Non-randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07277348 · PRK PLUS in thin cornea