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Enrolling by invitation NCT07275619

Normative Data for Cardiorespiratory Fitness in Healthy Adults

Observational Healthy Adults

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Healthy Adults. Basic parameters: 18 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Normative Data for Cardiorespiratory Fitness in Healthy Adults Using the Queen's College Step Test

Overview

Cardiorespiratory fitness (CRF) is a physical attribute which represents how effectively various bodily systems work together to transport and utilize oxygen to support muscular activity during prolonged, rhythmic, large-muscle, whole-body exercise. A key element associated with physical fitness is VO2max, which is referred to as cardiorespiratory fitness. Queen's college step test will be used to estimate the VO2max. This study will be cross sectional, normative study. Healthy adults aged 18-65 years from community setting will be recruited through non probability convenient sampling technique to collect data as per inclusion criteria. Sample size will be approximately 800, consist of equal ratio of males and females. Heart Rate, Recovery Heart Rate, VO2 max and METS will be calculated of each subject. Following equation is used to calculate VO2max, for females: VO2max = 65.81- \[0.1847× HR\] for males: VO2max = 111.33- \[0.42× HR\]. Data analysis will be conducted by using SPSS (Statistical Package for the Social Sciences) version 28.

Detailed description

Cardiorespiratory fitness (CRF) is a physical attribute which represents how effectively various bodily systems work together to transport and utilize oxygen to support muscular activity during prolonged, rhythmic, large-muscle, whole-body exercise. A key element associated with physical fitness is VO2max, which is referred to as cardiorespiratory fitness. Queen's college step test (reliability = 0.92, validity = 0.75) will be used to estimate the VO2max. The objectives of the study is to obtain the normative reference values for cardiorespiratory fitness in healthy pakistani adults.

This study will be cross sectional, normative study. Healthy adults aged 18-65 years from community setting will be recruited through non probability convenient sampling technique to collect data as per inclusion criteria. Sample size will be approximately 800, consist of equal ratio of males and females. Heart Rate, Recovery Heart Rate, VO2 max and METS will be calculated of each subject. Following equation is used to calculate VO2max, for females: VO2max = 65.81- \[0.1847× HR\] for males: VO2max = 111.33- \[0.42× HR\]. Demographics include Age (years), Height (m2), Weight (kg) and Body Mass Index (BMI kg/m2) will be measure for each subject.Data analysis will be conducted by using SPSS (Statistical Package for the Social Sciences) version 28.

Key words:

Adults, Cardiorespiratory fitness, Normative, Queen's college step test, VO2max

Primary outcome measures

  • Queen's college step test [Time frame: one time point]
  • pulse oximeter [Time frame: one time point]
  • Recovery Heart Rate [Time frame: one time point]
  • METS [Time frame: one time point]
Secondary outcome measures (3)
  • stadiometer [Time frame: one time point]
  • weighing machine [Time frame: one time point]
  • Body Mass Index [Time frame: one time point]

Eligibility criteria

Inclusion criteria

  • • Pakistani Adults of age group 18-65 according to ACSM's guidelines
  • Current healthy adults recruited by filling PAR\_Q test
  • IPAQ short form will be administered, Participants scoring moderate or high activity level will be selected to perform QCST
  • BMI ≥ 18.5 kg/m2 - ≤ 24.9 kg/m2
  • Resting spO2 >95%
  • Resting heart rate ≥60bpm and ≤100bpm
  • Mentally and physically fit adults without any physical, physiological and psychological issues

Exclusion criteria

Presence of any acute/chronic illness Any cardiovascular, respiratory, neuromuscular, psychological, musculoskeletal or orthopedic condition and history of surgery Individuals taking any medical treatment History of active smoking

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Pakistan · 1 center
  • Riphah International University, Lahore — Lahore

Publications

  • Kunutsor SK, Isiozor NM, Myers J, Seidu S, Khunti K, Laukkanen JA. Baseline and usual cardiorespiratory fitness and the risk of chronic kidney disease: A prospective study and meta-analysis of published observational cohort studies. Geroscience. 2023 Jun;45(3):1761-1774. doi: 10.1007/s11357-023-00727-3. Epub 2023 Jan 17. PMID 36646903
  • Rossi Neto JM, Tebexreni AS, Alves ANF, Smanio PEP, de Abreu FB, Thomazi MC, Nishio PA, Cuninghant IA. Cardiorespiratory fitness data from 18,189 participants who underwent treadmill cardiopulmonary exercise testing in a Brazilian population. PLoS One. 2019 Jan 9;14(1):e0209897. doi: 10.1371/journal.pone.0209897. eCollection 2019. PMID 30625200
  • Kaminsky LA, Arena R, Myers J. Reference Standards for Cardiorespiratory Fitness Measured With Cardiopulmonary Exercise Testing: Data From the Fitness Registry and the Importance of Exercise National Database. Mayo Clin Proc. 2015 Nov;90(11):1515-23. doi: 10.1016/j.mayocp.2015.07.026. Epub 2015 Oct 5. PMID 26455884
  • Ekblom-Bak E, Ekblom O, Andersson G, Wallin P, Soderling J, Hemmingsson E, Ekblom B. Decline in cardiorespiratory fitness in the Swedish working force between 1995 and 2017. Scand J Med Sci Sports. 2019 Feb;29(2):232-239. doi: 10.1111/sms.13328. Epub 2018 Nov 15. PMID 30351472
  • Hills AP, Jayasinghe S, Arena R, Byrne NM. Global status of cardiorespiratory fitness and physical activity - Are we improving or getting worse? Prog Cardiovasc Dis. 2024 Mar-Apr;83:16-22. doi: 10.1016/j.pcad.2024.02.008. Epub 2024 Feb 27. PMID 38417767
  • Sloan RA. Estimated Cardiorespiratory Fitness and Metabolic Risks. Int J Environ Res Public Health. 2024 May 16;21(5):635. doi: 10.3390/ijerph21050635. PMID 38791849
  • Dourado VZ, Nishiaka RK, Simoes MSMP, Lauria VT, Tanni SE, Godoy I, Gagliardi ART, Romiti M, Arantes RL. Classification of cardiorespiratory fitness using the six-minute walk test in adults: Comparison with cardiopulmonary exercise testing. Pulmonology. 2021 Nov-Dec;27(6):500-508. doi: 10.1016/j.pulmoe.2021.03.006. Epub 2021 May 4. PMID 33958319
  • Liu Y, Zhu J, Guo Z, Yu J, Zhang X, Ge H, Zhu Y. Estimated cardiorespiratory fitness and incident risk of cardiovascular disease in China. BMC Public Health. 2023 Nov 24;23(1):2338. doi: 10.1186/s12889-023-16864-5. PMID 38001416

Identifiers

NCT: NCT07275619 · nida naz

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗