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Enrolling by invitation NCT07269236

Prospective Real-World Study of Multimodal AI

Observational Pancancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Pancancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Prospective Real-World Study of a Multimodal Artificial Intelligence Model Across Disease Types

Overview

This project proposes to collect prospective multimodal data-such as pathology, imaging, and clinical information-and to perform integrative analyses. AI technologies can offer novel solutions for disease classification, tumor grading, histological subtyping, molecular subtyping, selection of chemotherapy regimens, risk stratification, treatment response prediction, report generation, and intelligent question-answering. This research provides important support for precision medicine and individualized treatment and has significant theoretical and practical implications. Conducting a prospective randomized controlled study better aligns with clinical application requirements and can accelerate the comprehensive deployment of AI systems.

Primary outcome measures

  • Area under ROC curve (AUC) [Time frame: Diagnostic evaluation will be performed within 1 week when the WSIs or CT are obtained]
Secondary outcome measures (2)
  • Specificity [Time frame: Diagnostic evaluation will be performed within 1 week when the WSIs or CT are obtained]
  • Sensitivity [Time frame: Diagnostic evaluation will be performed within 1 week when the WSIs or CT are obtained]

Eligibility criteria

Inclusion criteria

  • Age 18 years or older.
  • Patients with available digitized pathology slides, radiological imaging, and corresponding clinical data.

Exclusion criteria

1.Patients with missing data or specimens not meeting quality control requirements for analysis.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 2 centers
  • Nanfang Hospital, Southern Medical University — Guangzhou
  • Zhongshan City People's Hospital — Zhongshan

Identifiers

NCT: NCT07269236 · NFEC-2025-602

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗